Development of strategies to assist the movement of poorly permeable molecules across biological barriers has long been the goal of drug delivery science. In the last three decades, there has been an exponential increase in advanced drug delivery systems that aim to address this issue. However, most proprietary delivery technologies that have progressed to clinical development are based on perm…
Mitochondrial disease constitutes a complex and heterogeneous group of disorders resulting from a defect in mitochondrial respiratory chain (MRC) enzyme activity. In view of the dual regulation of the MRC, exercised by both the mitochondrial and nuclear genome, mutations in either mitochondrial or nuclear DNA can result in a MRC deficiency. Whilst a single organ can be affected, MRC disorders o…
The topic of entrepreneurial cognition has fascinated us and motivated our research over the last two decades. Although this research has resulted in publications in the top entrepreneurship, strategy, management, and psychology journals, we thought now would be a good time to pause, reflect on our work, and bring these individual pieces of the puzzle together to provide a cohesive big picture …
The hypothalamus is a small part of the brain located just below the thalamus on both sides of the third ventricle. (The ventricles are areas within the cerebrum that are filled with cerebrospinal fluid, and connect to the fluid in the spine.) It sits just inside the two tracts of the optic nerve, and just above (and intimately connected with) the pituitary gland.
The traditional knowledge and use of medicinal plant species from the plant family Asteraceae was reviewed for the treatment of several types of cancers in Aizawl District, Mizoram, Northeast India. Traditional healers and patients suffering from various cancers in the study area were interviewed with the help of local translators to congregate the information for the use of medicinal plant…
Entrepreneurship has a tremendous impact on the economic development of a country, so much that entrepreneurship is seen as a solution for the fast changing economic demands worldwide and has been recognized as a path to sustainable economic development. Despite recognition of entrepreneurship on the road to global economic development, a large body of research on the elements of entreprene…
this Handbook of Experimental Pharmacology on “High Density Lipoproteins – from biological understanding to clinical exploitation” contributing authors (members of COST Action BM0904/HDLnet) summarize in more than 20 chapters our current knowledge on the structure, function, metabolism and regulation of HDL in health and several diseases as well as the status of past and ongoing attempts …
Plant medicines are the original medicines that humans have always used. Many people continue to use plant medicines today including teas, coffee, chocolate, ginger, and other medicines. Traditional medicine is based on plant medicines and is the primary form of medicine for many people throughout the world. The current volume discusses traditional medicines and presents various plant medicines…
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