This book provides information on best practices and new thinking regarding the validation of alternative methods for toxicity testing. It covers the validation of experimental and computational methods and integrated approaches to testing and assessment. Validation strategies are discussed for methods employing the latest technologies such as tissue-on-a-chip systems, stem cells and transcript…
This volume presents the proceedings of the CLAIB 2014, held in Paraná, Entre Ríos, Argentina 29, 30 & 31 October 2014. The proceedings, presented by the Regional Council of Biomedical Engineering for Latin America (CORAL) offer research findings, experiences and activities between institutions and universities to develop Bioengineering, Biomedical Engineering and related sciences. The confe…
This book systematically summarizes the ideas and technologies used in urine proteome analysis. It argues that change is the core of biomarker definition since the body uses its homeostatic mechanisms to correct changes in the blood. This means that urine is probably a better source of biomarkers than blood. A roadmap to the urinary biomarker era is proposed, and researchers are reminded of the…
Cataract surgery is one of the most frequently performed procedure in the United States, and cataracts are a leading cause of visual impairment in the world. Glaucoma is also a very common eye disease with an expected 3.3 million Americans afflicted with primary open angle glaucoma by 2020. The coexistence of these two diseases is not uncommon and management of a cataract can have significant i…
This richly illustrated book is intended as a gold standard for the refractive surgeon. It complements the authors’ successful previous book, Management of Complications in Refractive Surgery, by providing detailed practical information on the management of specific cases. Worldwide leaders in the field document a wide range of challenging cases drawn from their own clinical practice. These c…
This book provides ophthalmic surgeons with a concise, clinical guide to performing the fundamentals steps in phacoemulsification cataract surgery. Clear diagrams, images, and videos are used throughout and the information can be adapted to a particular consultant’s own technique once the surgical principles are understood. The chapters serve as a modular framework that allows for safe, effec…
This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discuss…
This book reviews the surgical techniques currently employed for the management of astigmatism, with the aim of providing a clear, comprehensive, step-by-step guide that will help practitioners to optimize outcomes. The book is divided into two sections covering the cutting-edge surgical approaches in cataract and refractive patients. Renowned experts with many years of clinical experience desc…
This book summarizes the current knowledge on lens surgery. Not only are the surgical procedures described in detail, but experts share with the reader many useful practical tips for individual surgical steps to achieve the best possible surgical result. In addition to the focus on surgery, pre- and post-operative care and complication management is also discussed in detail and a systematic rev…
This book provides an in-depth analysis of one the of most popular medicinal plants—Echinacea a species that is native to only the US and Canada. There are nine Echinacea species and several roots and above-ground portions of these showy wildflowers have been used in herbal medicine as an immune stimulant and to reduce one’s chances of catching a cold. Considerable medical research supports…