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Tryptophan Metabolism: Implications for Biological Processes, Health and Disease
This book discusses the relationship between cellular immunity and tryptophan metabolism, as well as its products, serotonin and melatonin, in the development of several diseases and reappraises the common signal transduction pathways of the neurodegenerative diseases, carcinogenesis, immune tolerance, inflammation, hypersensitivity reactions, neuropsychiatric disorders, in addition to bacteria…
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- 978-3-319-15630-9
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Global Agricultural Workers from the 17th to the 21st Century
Agricultural workers have long been underrepresented in labour history. This volume aims to change this by bringing together a collection of studies on the largest group of the global work force. The contributions cover the period from the early modern to the present – a period when the emergence and consolidation of capitalism has transformed rural areas all over the globe. Three questions h…
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- 9789004529427
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Variance in Approach Toward a ‘Sustainable’ Coffee Industry in Costa Rica…
"The monograph considers influence over time of Fairtrade and Rainforest Alliance in 10 Costa Rican coffee farming communities. In-country perspectives and relevant historic and contemporary literature inform findings. Misaligned intentions to outcomes; different sustainability approaches; and variable influence is observed. There is opportunity to: consider when certifications are most useful;…
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- 9781911529798
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Treatment of Peritoneal Surface Malignancies State of the Art and Perspectives
This monograph summarizes state of the art knowledge regarding peritoneal surface malignancies, with in-depth description of treatment options and the results achieved to date. It explores the most challenging problems on the basis of the authors’ very extensive clinical experience and examines the most relevant clinical trials. A comprehensive summary is provided of all phase 2 studies (the …
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- 978-88-470-5711-1
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Practical Salesforce.com Development Without Code; Customizing Salesforce on …
Jika Anda menggaruk-garuk kepala menanggapi judul buku, Development without Code, Anda akan terkejut mengetahui bahwa ini sama sekali bukan sebuah paradoks. Sementara pengembangan tipikal membutuhkan pengetahuan tentang bahasa pemrograman tertentu, pembuatan aplikasi bisnis di dalamnya Salesforce.com tidak. Beberapa karyawan yang sangat cerdas di Salesforce.com telah menghabiskan ribuan jam bek…
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- 978-1-4842-0097-1
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- 004.6 WEI p
Translational Toxicology Defining a New Therapeutic Discipline
Bringing together a distinguished interdisciplinary team of contributors, this volume provides a comprehensive exploration of translational toxicology—a systematic approach to developing therapeutic interventions that can protect against, mitigate, or reverse the effects of exposures. In particular, the book addresses modes of action and biomarkers, developmental risks of exposures, and poten…
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- 978-3-319-27449-2
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Translational Research Methods for Diabetes, Obesity and Cardiometabolic Drug…
The world is beset by a pandemic of obesity and type 2 diabetes and the need for new drugs is startlingly clear; recent years have seen a huge increase in research activity to fill this gap. The development of new drugs for diabetes and obesity must be founded upon a sound appreciation of the pathophysiology of these common disorders. The dual defects of insulin resistance and impaired insulin …
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- 978-1-4471-4920-0
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Translational Neuropsychopharmacology
This book covers wide areas of animal and human psychopharmacology with clinical utility in the treatment of psychiatric and neurological (e.g Alzheimer's disease) disorders. The main theme is to develop a new paradigm for drug discovery that questions the claim that animal models or assays fail adequately to predict Phase 3 clinical trials. A new paradigm is advocated that stresses the importa…
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- 978-3-319-33913-9
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The Evolution of Applied Harmonic Analysis
A sweeping exploration of essential concepts and applications in modern mathematics and science through the unifying framework of Fourier analysis! This unique, extensively illustrated book, accessible to specialists and non-specialists, describes the evolution of harmonic analysis, integrating theory and applications in a way that requires only some general mathematical sophistication and know…
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- 978-0817641252
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Translating Molecular Biomarkers into Clinical Assays Techniques and Applica…
This handbook covers established and advanced techniques for biomarker analysis, such as guidelines and strategies for assay validation methods; different mathematical models that are necessary in contemporary drug discovery and development; and evaluation of new cytometry methods. Expertly curated by two practicing professionals in drug development and biotherapeutics, individual chapters are …
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- 978-3-319-40793-7
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