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Tactics in Contemporary Drug Design
Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemist…
- Edition
- -
- ISBN/ISSN
- 978-3-642-55041-6
- Collation
- XII, 394
- Series Title
- Topics in Medicinal Chemistry
- Call Number
- -
Modeling in Biopharmaceutics, Pharmacokinetics and Pharmacodynamics
The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this new second edition book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. The book is divided into four parts; the first deals with the fundamental princ…
- Edition
- 2
- ISBN/ISSN
- 978-3-319-27596-3
- Collation
- XXII, 483
- Series Title
- Interdisciplinary Applied Mathematics
- Call Number
- -
Basic and Clinical Toxicology of Mustard Compounds
This book offers a practical guide to the clinical management of sulphur and nitrogen mustard exposure including information on the history, pharmacology and toxicology of mustard compounds (MC). Basic and Clinical Toxicology of Mustard Compounds details the many resulting complications of sulphur mustard (SM) poisoning such as respiratory, Dermatological, Ophthalmological and Psychiatric. …
- Edition
- -
- ISBN/ISSN
- Springer Cham
- Collation
- -
- Series Title
- -
- Call Number
- 615.4
Methods of Applied Mathematics with a Software Overview
This textbook, now in its second edition, provides students with a firm grasp of the fundamental notions and techniques of applied mathematics as well as the software skills to implement them. The text emphasizes the computational aspects of problem solving as well as the limitations and implicit assumptions inherent in the formal methods. Readers are also given a sense of the wide variety of p…
- Edition
- 2
- ISBN/ISSN
- 978-3-319-43369-1
- Collation
- XVII, 781
- Series Title
- Applied and Numerical Harmonic Analysis
- Call Number
- -
Translational Toxicology
Bringing together a distinguished interdisciplinary team of contributors, this volume provides a comprehensive exploration of translational toxicology—a systematic approach to developing therapeutic interventions that can protect against, mitigate, or reverse the effects of exposures. In particular, the book addresses modes of action and biomarkers, developmental risks of exposures, and poten…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-27449-2
- Collation
- XV, 380
- Series Title
- Molecular and Integrative Toxicology
- Call Number
- -
Translational Research Methods for Diabetes, Obesity and Cardiometabolic Drug…
The world is beset by a pandemic of obesity and type 2 diabetes and the need for new drugs is startlingly clear; recent years have seen a huge increase in research activity to fill this gap. The development of new drugs for diabetes and obesity must be founded upon a sound appreciation of the pathophysiology of these common disorders. The dual defects of insulin resistance and impaired insulin …
- Edition
- 1
- ISBN/ISSN
- 978-1-4471-7032-7
- Collation
- XII, 312
- Series Title
- -
- Call Number
- -
Translational Neuropsychopharmacology
This book covers wide areas of animal and human psychopharmacology with clinical utility in the treatment of psychiatric and neurological (e.g Alzheimer's disease) disorders. The main theme is to develop a new paradigm for drug discovery that questions the claim that animal models or assays fail adequately to predict Phase 3 clinical trials. A new paradigm is advocated that stresses the importa…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-33911-5
- Collation
- XII, 498
- Series Title
- Current Topics in Behavioral Neurosciences
- Call Number
- -
Translating Molecular Biomarkers into Clinical Assays
This handbook covers established and advanced techniques for biomarker analysis, such as guidelines and strategies for assay validation methods; different mathematical models that are necessary in contemporary drug discovery and development; and evaluation of new cytometry methods. Expertly curated by two practicing professionals in drug development and biotherapeutics, individual chapters are …
- Edition
- 1
- ISBN/ISSN
- 978-3-319-40793-7
- Collation
- XIII, 212
- Series Title
- AAPS Advances in the Pharmaceutical Sciences Series
- Call Number
- -
Transglutaminases
This book presents basic and extensive information on the physiological and pathological significance of the protein-modifying enzymes, transglutaminases, which are involved in multiple biological events by catalyzing a unique and important posttranslational modification reaction, cross-linking of proteins, and interacting with a large number of proteins inside and outside of cells. Although se…
- Edition
- 1
- ISBN/ISSN
- 978-4-431-55823-1
- Collation
- VIII, 391
- Series Title
- -
- Call Number
- -
Toxic Trauma
Winner of BMA Medical Book Award, Highly Commended in Public Health Written for medical professionals, this book provides a concise reference with clear guidelines on how to manage both the victims of chemical agent exposure and the site of the incident. David Baker considers the nature and basic science of the hazards faced as well as the practical management of persons exposed to chemicals a…
- Edition
- 2
- ISBN/ISSN
- 978-3-319-40916-0
- Collation
- XXIII, 238
- Series Title
- -
- Call Number
- -
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