This book discusses in detail molecular, mycobiont culture, biomonitoring and bioprospection of lichens, providing insights into advances in different fields of lichenology by applying modern techniques and approaches and examining how their application has enhanced or changed classical approaches. It offers a valuable resource, especially for beginners, students and researchers from different …
The objective of this book is to catalyze the application of genomics to the diagnosis and treatment of oral diseases by comprehensively presenting focused discussions on the current state of knowledge. The first section book provides basic information about genetics, genomics and personalized medicine and the informatical methods available to apply and organize genetic data so that it has clin…
This book describes important advances in our understanding of how environmental conditions affect cardiac gene expression through epigenetic mechanisms. Further, it discusses the roles of chromatin modifications (in particular DNA methylation and histone modifications) and of chromatin regulators in the context of cardiac diseases. The book provides readers with an overview of our current unde…
The field of neuroendocrinology has extended from the initial interest in the hypothalamic control of pituitary secretion to embrace multiple reciprocal interactions between the central nervous system (CNS) and endocrine systems in the coordination of homeostasis and various physiological responses from adaptation to disease. Most recently, epigenetic mechanisms were recognized for their role i…
The field of neuroendocrinology has extended from the initial interest in the hypothalamic control of pituitary secretion to embrace multiple reciprocal interactions between the central nervous system and endocrine systems in the coordination of homeostasis and various physiological responses from adaptation to disease. Most recently, epigenetic mechanisms were recognized for their role in the …
The ability of a single genome to give rise to hundreds of functionally distinct cell type programs is in itself remarkable. Pioneering studies over the past few decades have demonstrated that this plasticity is retained throughout development, a phenomenon of epigenetic programming and reprogramming that remains one of the most fascinating areas of modern biology, with major relevance to human…
This book presents epigenetics research as a new way of looking at genetics. Topics range from basic epigenetics mechanisms to development of cells and organisms and the biological basis of diseases. In addition the book focuses on immunology and the role of viruses in epigenetics. The last part of the book highlights proteins and peptides as epigenetic modulators.
This book presents a long-term study in genetic isolates of indigenous small ethnics of Dagestan, located in the North-East part of Caucasus in Russia. Dagestan is characterized by extreme cultural and linguistic differences in a small geographic area and contains 26 indigenous ethnic groups. According to archeological data these indigenous highland ethnics have been living in the same area for…
This book provides an introduction to the latest gene mapping techniques and their applications in biomedical research and evolutionary biology. It especially highlights the advances made in large-scale genomic sequencing. Results of studies that illustrate how the new approaches have improved our understanding of the genetic basis of complex phenotypes including multifactorial diseases (e.g., …
This comprehensive volume explores human genetic engineering its pre-clinical and clinical applications, current developments, and as treatment for hereditary diseases. It presents and evaluates the most recent advances in the understanding of mammalian host DNA repair mechanisms, such as double-strand break induced gene targeting and mutagenesis, the development of zinc-finger nucleases, genom…