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Rethinking Youth Wellbeing
This volume offers a critical rethinking of the construct of youth wellbeing, stepping back from taken-for-granted and psychologically inflected understandings. Wellbeing has become a catchphrase in educational, health and social care policies internationally, informing a range of school programs and social interventions and increasingly shaping everyday understandings of young people. Drawing …
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- 978-981-287-188-6
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Retail Supply Chain Management
This new edition focuses on three crucial areas of retail supply chain management: (1) empirical studies of retail supply chain practices, (2) assortment and inventory planning and (3) integrating price optimization into retail supply chain decisions. The book has been fully updated, expanding on the distinguishing features of the original, while offering three new chapters on recent topics whi…
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- 978-1-4899-7742-7
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Resistance to Photodynamic Therapy in Cancer
This volume provides a comprehensive review of resistance induced by photodynamic therapy (PDT) in tumor cells. Understanding the underlying mechanisms in this process leads to the improvement of therapeutic modality, in combination with chemotherapy, immunotherapy, and radiotherapy. Photodynamic therapy is a minimally invasive therapeutic procedure that can exert a selective or preferential cy…
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- 978-3-319-12730-9
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Resistance to Targeted ABC Transporters in Cancer
This critical review volume explores the theme of ABC transporters in the context of basic cancer research and its role in drug-resistant tumors. The chapters provided complement basic research by including investigations from translational applications to clinical oncology. The development of resistance is a major obstacle in cancer chemotherapy and the field has been moving rapidly in terms o…
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Resistance to Targeted Therapies Against Adult Brain Cancers
This volume will bring together a review of research being carried out by international experts in this field, detailing treatment and research approaches in several forms of malignant brain tumors. These include glioblastoma (GBM), a highly aggressive and fatal form of astrocytoma which accounts for 80% of newly diagnosed brain tumor patients per year, and meningioma, of which 10% are malignan…
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- 978-3-319-46505-0
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Resistance to Tyrosine Kinase Inhibitors
The volume will serve as a primer on tyrosine kinase signaling and its importance in cancer. The volume will first introduce the common denominators of small-molecule and antibody-derived inhibitors, as well as the general phenomenon of resistance. The volume will then detail resistance to the most commonly used classes of tyrosine kinase inhibitors, and will focus specific chapters on resistan…
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- 978-3-319-46091-8
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Respiratory Carcinogenesis
The book blends basic and clinical research on respiratory carcinogensis. The contributions tackle a variety of respiratory-related cancers, notably non-small cell lung carcinoma, pleural mesothelioma, mediastinal tumors, or larynx cancer. The focus is on the search for novel molecular markers, derived from easily accessible tissues in clinical settings, such as the serum or bronchoalveolar lav…
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- 978-3-319-16922-4
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Resistance of Cancer Cells to CTL-Mediated Immunotherapy
This comprehensive volume explores the latest research on the mechanisms of resistance in cancer cells to CTL-mediated immunotherapy. Chapter topics discuss cell-mediated immunity as the result of cytotoxic T-lymphocytes (CTL) directed specifically against cancer cells. In addition, the volume reviews how CTL mediate the cytotoxic activity, in large part, by the indication of apoptosis; hence, …
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- 978-3-319-17807-3
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Resistance to Aromatase Inhibitors in Breast Cancer
Aromatase Inhibitors (AIs) treat postmenopausal estrogen receptor positive tumours, which constitute the majority of breast cancer patients. This comprehensive volume brings together the current knowledge from different relevant areas, including molecular mechanisms and translational aspects of drug resistance in AIs. Topics covered include research, experimental , and clinical data specificall…
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- 978-3-319-17971-1
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Resistance to Immunotoxins in Cancer Therapy
This book will be a guide to understanding resistance against targeted therapeutic approaches for cancer using immunotoxins. It contains a detailed review of the history and development of targeted therapy. As well, it includes an in-depth description of the molecular and cellular mechanisms involved in cancer resistance and several novel methods to overcome resistance. Each chapter discusses d…
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- Ed. 1
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- 978-3-319-17275-0
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