The objective of this volume is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist’s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound’s physio…
High Performance Computing (HPC) remains a driver that offers huge potentials and benefits for science and society. However, a profound understanding of the computational matters and specialized software is needed to arrive at effective and efficient simulations. Dedicated software tools are important parts of the HPC software landscape, and support application developers. Even though a tool is…
Numerical simulation and modelling using High Performance Computing has evolved into an established technique in academic and industrial research. At the same time, the High Performance Computing infrastructure is becoming ever more complex. For instance, most of the current top systems around the world use thousands of nodes in which classical CPUs are combined with accelerator cards in order …
One last comment concerns the fundamental contributions of Fourier analysis to quantum physics: Quantum mechanics and quantum field theory.
The work addresses communication networks established over radio equipped vehicles in our everyday road traffic, so called Vehicular Ad Hoc Networks (VANETs), and discusses their impact on two major goals, namely traffic safety and traffic efficiency. For both objectives, the thesis proposes an appropriate modeling of the essential building blocks Traffic, Communication and Application and enab…
First published in 1953, as the second edition of a 1928 original, this book supplies a detailed bibliography of Dr William Harvey, who described the workings of the circulatory system in his revolutionary 1628 treatise, De Motu Cordis. Keynes notes the various editions and translations of Harvey's three key works as well as miscellaneous writings and anthologies and their locations in librarie…
First published in 1826, at a time when the earth sciences were in a state of confusion and controversy, this pioneering study of volcanic action by Charles Daubeny (1795–1867) was significant in promoting the scientific method and the science of geology, at the same time establishing the author's international reputation. Having studied medicine, Daubeny increasingly turned his attention to …
This book examines the reasons behind the resonant amplification of seismic and ocean waves that have the capacity to destroy cities and ocean-going vessels. Using Charles Darwin's important geophysical research as a starting point, it provides insights into the interaction between earthquakes with volcanoes, seaquake, and tsunami formation. In particular, the author details the observations th…
Charles Darwin has been extensively analysed and written about as a scientist, Victorian, father and husband. However, this is the first book to present a carefully thought out pedagogical approach to learning that is centered on Darwin?s life and scientific practice. The ways in which Darwin developed his scientific ideas, and their far reaching effects, continue to challenge and provoke conte…
This book presents multivariate time series methods for the analysis and optimal control of feedback systems. Although ships’ autopilot systems are considered through the entire book, the methods set forth in this book can be applied to many other complicated, large, or noisy feedback control systems for which it is difficult to derive a model of the entire system based on theory in that subj…