The objective of this volume is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist’s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound’s physio…
The late eighteenth century saw Manchester and its surrounding areas undergo significant change as industrialisation fuelled urbanisation and population growth. In this classic 1795 account, the physician and prolific writer John Aikin (1747–1822) gathers together information on the settlements at the heart of manufacturing and trade in north-west England, covering the vital network of waterw…
What does pleasure have to do with morality? What role, if any, should intuition have in the formation of moral theory? If something is ‘simulated’, can it be immoral? This accessible and wide-ranging textbook explores these questions and many more. Key ideas in the fields of normative ethics, metaethics and applied ethics are explained rigorously and systematically, with a vivid writing st…
This textbook is written by a group of select experts with a focus on different aspects of the design process, from creation to production.Traditionally referred to as graphic design, communication design is the process by which messages and images are used to convey information to a targeted audience. It is within this spectrum that this textbook addresses the many steps of creating and then p…
Thomas Falkner (1707–84), one-time pupil of both Richard Mead and Isaac Newton, was an English Jesuit missionary who lived for nearly forty years in South America until 1767, when he returned to England following the Jesuits' expulsion from Córdoba. Originally published in 1774 in the hope that it 'might be of some public utility, and might also afford some amusement to the curious', this is…
This is the first textbook to cover the essential aspects of the topic at a level accessible to students. While focusing on applications in solid earth geophysics, the book also includes excursions into helioseismology, thereby highlighting the strong affinity between the two fields. The book provides a comprehensive introduction to seismic tomography, including the basic theory of wave propaga…
Sir Robert Hermann Schomburgk (1804–1865) was a German-born surveyor and traveller. In 1835–1839 he explored British Guiana for the Royal Geographical Society. In 1840 he was appointed to define its boundaries with Brazil, as Brazilian encroachments were wiping out native tribes. His report to the Colonial Office was published as A Description of British Guiana, Geographical and Statistical…
This book reviews research on Dan Shen, compiles data from clinical trials and biological experiments, and summarizes the latest research advances. It covers the medicinal herb, herbal pieces, and new proprietary drugs that contain it; it also covers simple and compound, traditional and contemporary formulas, and addresses a broad range of subjects, including: standardized cultivation; biodiver…
This thesis presents experimental and theoretical investigations of the connection between the time asymmetry in the short-time evolution of particle clusters and the intrinsic irreversibility of turbulent flows due to the energy cascade. The term turbulence describes a special state of a continuous medium in which many interacting degrees of freedom are excited. One of the interesting phen…
This book documents the state of the art in the use of remote sensing to address time-sensitive information requirements. Specifically, it brings together a group of authors who are both researchers and practitioners, who work toward or are currently using remote sensing to address time-sensitive information requirements with the goal of advancing the effective use of remote sensing to supply t…