David Armstrong's book is a contribution to the philosophical discussion about possible worlds. Taking Wittgenstein's Tractatus as his point of departure, Professor Armstrong argues that nonactual possibilities and possible worlds are recombinations of actually existing elements, and as such are useful fictions. There is an extended criticism of the alternative-possible-worlds approach champion…
Nietzsche looms over modern literature and thought; according to Gottfried Benn, 'everything my generation discussed, thought through innerly; one could say: suffered; or one could even say: took to the point of exhaustion - all of it had already been said . . . by Nietzsche; all the rest was just exegesis.' Nietzsche's influence on intellectual life today is arguably as great; witness the vari…
In this book, we discuss the changing medical and public profile of fungal infections in the period 1850–2000. We consider four sets of diseases: ringworm and athlete’s foot (dermatophytosis); thrush or candidiasis (infection with Candida albicans); endemic, geographically specific infections in North America (coccidioidomycosis, blastomycosis and histoplasmosis) and mycotoxins; and aspergi…
Orientalist and colonial administrator John Crawfurd (1783–1868) published this work in 1856. He went to Calcutta as an assistant surgeon in the East India Company, then moved into administration, accompanying political missions to Java, Bali and Celebes, and heading missions to Siam, Vietnam and Burma. Retiring to England in 1828, Crawfurd became a Fellow of the Royal Society and President o…
The mechanistic basis of chronic inflammation remains unclear. The research sheds new light on the immune cells expressing the activation markers HLA-DR and regulatory T cells (Tregs) and the cells expressing Siglec receptors as being key players in the immune system responsiveness to antigens and thus in lung tissue damage of chronic inflammation. The results help understand the mechanisms of …
The aim of this book is to advocate and promote network models of linguistic systems that are both based on thorough mathematical models and substantiated in terms of linguistics. In this way, the book contributes first steps towards establishing a statistical network theory as a theoretical basis of linguistic network analysis the boarder of the natural sciences and the humanities. This book a…
Rear-Admiral James Burney (1750–1821), brother of the novelist Fanny Burney and son of the musicologist Dr Charles Burney, is best known for his five-volume compilation of voyages in the Pacific Ocean (also reissued in this series). He began his maritime career at the age of ten, as a captain's servant. Five years later he became a naval officer, and from 1772 to 1780 served on Cook's second …
In this volume, the author investigates and argues for, a particular answer to the question: What is the right way to logically analyze modalities from natural language within formal languages? The answer is: by formalizing modal expressions in terms of predicates. But, as in the case of truth, the most intuitive modal principles lead to paradox once the modal notions are conceived as predicate…
This book focuses on thielocin B1 (TB1), which was found to be an inhibitor of protein–protein interactions (PPIs) of proteasome assembling chaperone (PAC) 3 homodimer, and elucidates the mechanism by nuclear magnetic resonance (NMR) studies. Interfaces of PPIs recently have been expected to be novel therapeutic targets, while it is difficult to apply conventional methodology based on lock an…
This short work, featuring a number of attractive engravings, traces an abortive expedition to the Canadian Arctic. George Francis Lyon (1795–1832), naval officer and explorer, had accompanied William Parry on a previous expedition in search of the North-West Passage. In 1824 Lyon was instructed to return to Repulse Bay and to explore the mainland. Unfavourable weather conditions forced Lyon …