Residual Stress, Thermomechanics& Infrared Imaging, Hybrid Techniques and Inverse Problems, Volume 9 of the Proceedings of the 2015SEM Annual Conference & Exposition on Experimental and Applied Mechanics, the ninth volume of nine from the Conference, brings together contributions to this important area of research and engineering. The collection presents early findings and case studies on a wid…
This book establishes a new, holistic framework for disaster recovery and mitigation, providing a multidisciplinary perspective on the field of risk management strategies and societal and communal resilience. Going beyond narrow approaches that are all too prevalent in the field, this work builds on an optimum combination of community-level networks, private market mechanisms and state-based as…
This important text addresses the latest issues in end-to-end resilient routing in communication networks. The work highlights the main causes of failures of network nodes and links, and presents an overview of resilient routing mechanisms, covering issues related to the Future Internet (FI), wireless mesh networks (WMNs), and vehicular ad-hoc networks (VANETs). Features: discusses FI architect…
This Springer Brief introduces wireless sensor networks (WSNs) and the need for resilient WSN operations in application domains. It presents traditional approaches of providing resilient operation of WSNs to ensure continuity of data delivery even when some network sensors fail. The pros and cons of each these approaches are discussed. Also included is an overview of network coding basics, a…
This comprehensive volume explores the latest research on the mechanisms of resistance in cancer cells to CTL-mediated immunotherapy. Chapter topics discuss cell-mediated immunity as the result of cytotoxic T-lymphocytes (CTL) directed specifically against cancer cells. In addition, the volume reviews how CTL mediate the cytotoxic activity, in large part, by the indication of apoptosis; hence, …
Aromatase Inhibitors (AIs) treat postmenopausal estrogen receptor positive tumours, which constitute the majority of breast cancer patients. This comprehensive volume brings together the current knowledge from different relevant areas, including molecular mechanisms and translational aspects of drug resistance in AIs. Topics covered include research, experimental , and clinical data specificall…
This book will be a guide to understanding resistance against targeted therapeutic approaches for cancer using immunotoxins. It contains a detailed review of the history and development of targeted therapy. As well, it includes an in-depth description of the molecular and cellular mechanisms involved in cancer resistance and several novel methods to overcome resistance. Each chapter discusses d…
This book focuses on group sequential methods for clinical trials with co-primary endpoints based on the decision-making frameworks for: (1) rejecting the null hypothesis (stopping for efficacy), (2) rejecting the alternative hypothesis (stopping for futility), and (3) rejecting the null or alternative hypothesis (stopping for either futility or efficacy), where the trial is designed to evaluat…
This volume presents a number of controversial cases of enforced medical treatment from around the globe, providing for the first time a common, biopolitcal framework for all of them. Bringing together all these real cases guarantees that a new, more complete understanding of the topic will be within grasp for readers unacquainted with the aspects involved in these cases. On the one hand, reade…
This book constitutes the proceedings of the 19th International Conference on Theory and Practice of Digital Libraries, TPDL 2015, held in Poznań, Poland, in September 2015. The 22 full papers and 14 poster and demo papers presented in this volume were carefully reviewed and selected from 61 submissions. They were organized in topical sections named: interoperability and information integra…