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Translating Molecular Biomarkers into Clinical Assays Techniques and Applica…
This handbook covers established and advanced techniques for biomarker analysis, such as guidelines and strategies for assay validation methods; different mathematical models that are necessary in contemporary drug discovery and development; and evaluation of new cytometry methods. Expertly curated by two practicing professionals in drug development and biotherapeutics, individual chapters are …
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- 978-3-319-40793-7
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Transient Changes in Molecular Geometries and How to Model Them Simulating C…
This thesis examines various aspects of excess excitation energy dissipation via dynamic changes in molecular structure, vibrational modes and solvation. The computational work is carefully described and the results are compared to experimental data obtained using femtosecond spectroscopy and x-ray scattering. The level of agreement between theory and experiment is impressive and provides both …
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- 978-3-319-18747-1
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Transglutaminases Multiple Functional Modifiers and Targets for New Drug Dis…
This book presents basic and extensive information on the physiological and pathological significance of the protein-modifying enzymes, transglutaminases, which are involved in multiple biological events by catalyzing a unique and important posttranslational modification reaction, cross-linking of proteins, and interacting with a large number of proteins inside and outside of cells. Although se…
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- 978-4-431-55825-5
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Transdisciplinary Professional Learning and Practice
This book presents thinking about and through transdisciplinary and professional development as an educative process. Rather than focusing on the delineation of the approaches offered, an analysis of these contributions points to commonality in those problems that benefit from a transdisciplinary perspective. The core elements of transdisciplinarity can lead to what might be called metanoia …
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- 978-3-319-11590-0
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The Essential Guide to N-of-1 Trials in Health
N-of-1 trials, a type of individualized randomized controlled trial, are relevant to almost every discipline in medicine and psychology. They can tell the clinician with precision whether a treatment works in that individual, which distinguishes from the information available from most other trial designs. They have the potential to revolutionize the way clinical medicine is practiced. Whet…
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- 1
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- 978-94-017-7200-6
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- XI, 245
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The Empirical Validation of House Energy Rating (HER) Software for Lightweigh…
This book reports on the first empirical validation of “AccuRate,” Australia’s national benchmark software tool for house energy ratings. The validation was conducted by the University of Tasmania in collaboration with Forest and Wood Products Australia, the Australian Government, the CSIRO and industry partners. The study presented here describes the results of graphical and statistical …
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- 1
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- 978-3-319-14337-8
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- XIX, 344, 236 b/w illustrations, 60 illustrations in colour
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- Springer Theses
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The Emerging Quantum
This monograph presents the latest findings from a long-term research project intended to identify the physics behind Quantum Mechanics. A fundamental theory for quantum mechanics is constructed from first physical principles, revealing quantization as an emergent phenomenon arising from a deeper stochastic process. As such, it offers the vibrant community working on the foundations of quantum …
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- 978-3-319-34792-9
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- XIII, 366, 9 b/w illustrations
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The Electric Theories of J. Clerk Maxwell
In this volume Pierre Duhem first gives an overview of 19th century electricity and magnetism. Next, he applies his keen historical, philosophical, and physical intuition to critiquing Maxwell’s theories, especially his electromagnetic theory of light and the ad hoc introduction of displacement current, which he considers too much a product of the “esprit de géométrie” than the “espri…
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- 978-3-319-18515-6
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- XV, 185, 1 b/w illustrations
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- Boston Studies in the Philosophy and History of Science
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The Effects of Noise on Aquatic Life II
The meeting of Aquatic Noise 2013 will introduce participants to the most recent research data, regulatory issues and thinking about effects of man-made noise and will foster critical cross-disciplinary discussion between the participants. Emphasis will be on the cross-fertilization of ideas and findings across species and noise sources. As with its predecessor, The Effects of Noise on Aquatic …
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- 978-1-4939-2981-8
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- XXX, 1292, 97 b/w illustrations, 138 illustrations in colour
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- Advances in Experimental Medicine and Biology
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The Educational Significance of Human and Non-Human Animal Interactions
The Educational Significance of Human and Non-Human Animal Interactions explores human animal/non-human animal interactions from different disciplinary perspectives, from education policy to philosophy of education and ecopedagogy. The authors refute the idea of anthropocentrism (the belief that human beings are the central or most significant species on the planet) through an ethical investiga…
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- 978-1-137-50525-5
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- XIII, 234
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