The objective of this volume is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist’s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound’s physio…
This text provides the reader with the necessary technical tools and background to reach the frontiers of research without the introduction of too many extraneous concepts. Detailed and accessible proofs are included, as are a variety of exercises and problems. The two new chapters in this second edition are devoted to two topics of much current interest amongst functional analysts: Greedy appr…
The techniques presented here are useful for solving mathematical contest problems in algebra and analysis. Most of the examples and exercises that appear in the book originate from mathematical Olympiad competitions around the world. In the first four chapters the authors cover material for competitions at high school level. The level advances with the chapters. The topics explored include po…
This book combines issues several critical ones in the energy field (low-energy technologies, renewable energies such as the hydrogen economy, and geothermal energy). Moving towards a more sustainable world requires a complete revolution in the way we manage energy and resources. However, from an academic perspective, this theme is so broad that most educators and researchers tend to focus o…
This book constitutes the proceedings of the 15th International Conference on Transport Systems Telematics, TST 2015, held in Wrocław, Poland, in April 2015. The 35 revised full papers and two short papers included in this volume were carefully reviewed and selected from 115 submissions. The papers provide an overview of solutions being developed in the fields of transport telematics and inte…
High Performance Computing (HPC) remains a driver that offers huge potentials and benefits for science and society. However, a profound understanding of the computational matters and specialized software is needed to arrive at effective and efficient simulations. Dedicated software tools are important parts of the HPC software landscape, and support application developers. Even though a tool is…
This book focuses on analysis and design problems for high-order linear time-invariant (LTI) swarm systems (multi-agent systems) to achieve consensus, formation, containment and formation-containment. As a first step, the concepts of practical consensus and formation-containment are introduced. Unlike previous research, the formation in this book can be time-varying. A general framework for con…
The Web has evolved from an information sharing medium to a wide-scale environment for sharing capabilities or services. Currently, URLs not only point to documents and images, but are also used to invoke services that potentially change the state of the Web. Major online organizations today, such as Amazon, PayPal and FedEx, provide services for users and consumers. They also allow third-party…
The late eighteenth century saw Manchester and its surrounding areas undergo significant change as industrialisation fuelled urbanisation and population growth. In this classic 1795 account, the physician and prolific writer John Aikin (1747–1822) gathers together information on the settlements at the heart of manufacturing and trade in north-west England, covering the vital network of waterw…
This book is a survey of the theory of formal deformation quantization of Poisson manifolds, in the formalism developed by Kontsevich. It is intended as an educational introduction for mathematical physicists who are dealing with the subject for the first time. The main topics covered are the theory of Poisson manifolds, star products and their classification, deformations of associative algebr…