This monograph describes the progress in neuropathological HD research made during the last century, the neuropathological hallmarks of HD and their pathogenic relevance. Starting with the initial descriptions of the progressive degeneration of the striatum as one of the key events in HD, the worldwide practiced Vonsattel HD grading system of striatal neurodegeneration will be outlined. Correla…
These volumes will provide readers with a contemporary overview of current research on nicotine psychopharmacology and its role in tobacco dependence from leaders in this field of research and will hopefully prove valuable to those who are developing their own research programmes in this important topic.
The success of a BCI system depends as much on the system itself as on the user’s ability to produce distinctive EEG activity. BCI systems can be divided into two groups according to the placement of the electrodes used to detect and measure neurons firing in the brain. These groups are: invasive systems, electrodes are inserted directly into the cortex are used for single cell or multi unit …
This book describes ten of the most promising brain-computer-interface (BCI) projects to have emerged in recent years. BCI research is developing quickly, with many new ideas, research groups, and improved technologies. BCIs enable people to communicate just by thinking – without any movement at all. Several different groups have helped severely disabled users communicate with BCIs, and BCI t…
Stemming from a 2012 conference entitled Brain Degenerations and Emerging Mental Health Challenges in Sub-Saharan Africa, this book is aimed at both the general practitioner interested in CNS disorders, and the specialist who would like to know more about CNS pathology in Africa. By employing a broad defi nition of what brain degeneration means, the authors are able to touch upon everything fro…
The main focus of this monograph on whistled speech is the result of a worldwide inquiry primarily based on the author’s unprecedented fieldwork and laboratory experience. The different questions raised by the origin and the evolution of whistled forms of languages are also explored, including the role of environmental constraints in the emergence of whistled speech, their phonetic and phonol…
The proposed book investigates brain asymmetry from the perspective of functional neural systems theory, a foundational approach for the topic. There is currently no such book available on the market and there is a need for a neuroscience book, with a focus on the functional asymmetry of these two integrated and dynamic brains using historical and modern clinical and experimental research findi…
Empirical data on neural control of motor action and perception have not yet been put into the context of a coherent theory. Dr. Feldman's goal for the proposed book is to illustrate that the field is now at a stage where the data can be used to formulate some core principles that underlie action and perception and to present the foundation of a scientific theory of motor control. Dr. Feldman i…
The proposed book will act as a guide for scientists and clinicians to the unique information that MRS can provide. It will be a comprehensive overview of clinical and pre-clinical MRS applications and potential clinical utility of MRS biomarkers in degenerative brain diseases from leading experts in the field. MRS has proven to be a powerful complementary tool to MRI for the diagnosis and moni…
A number of leading experts in neuroscience including intermediary metabolism, enzymology and transporter physiology have contributed to this book which provides comprehensive discussions of these different aspects of the functional importance of the glutamate-glutamine cycle coupling homeostasis of glutamatergic, excitatory neurotransmission to basic aspects of brain energy metabolism. This bo…