The Forest of the Lacandon Maya: An Ethnobotanical Guide, with active links to audio-video recordings, serves as a comprehensive guide to the botanical heritage of the northern Lacandones. Numbering fewer than 300 men, women, and children, this community is the most culturally conservative of the Mayan groups. Protected by their hostile environment, over many centuries they maintain autonomy fr…
The real world is perceived and broken down as data, models and algorithms in the eyes of physicists and engineers. Data is noisy by nature and classical statistical tools have so far been successful in dealing with relatively smaller levels of randomness. The recent emergence of Big Data and the required computing power to analyse them have rendered classical tools outdated and insufficient. T…
This textbook explores both the theoretical foundation of the Finite Volume Method (FVM) and its applications in Computational Fluid Dynamics (CFD). Readers will discover a thorough explanation of the FVM numerics and algorithms used for the simulation of incompressible and compressible fluid flows, along with a detailed examination of the components needed for the development of a collocated u…
The volume presents, in a synergistic manner, significant theoretical and practical contributions in the area of social media reputation and authorship measurement, visualization, and modeling. The book justifies and proposes contributions to a future agenda for understanding the requirements for making social media authorship more transparent. Building on work presented in a previous volume of…
This book provides a comprehensive review of the latest advances in translational pain and itch research, and presents the cutting-edge developments in the study of our two principal, yet most mysteries sensations. Despite the slow progress in the discovery of effective therapies for chronic pain and pruritus, scientists around the globe now have a better understanding of why and how these cond…
Translational Research is the interface between basic science and human clinical application, including the entire process from animal studies to human clinical trials (phases I, II, and III). Translational Research moves promising basic science results from the laboratory to bedside application. Yet, this transition is often the least-defined, least-understood part of the research process. Mos…
The world is beset by a pandemic of obesity and type 2 diabetes and the need for new drugs is startlingly clear; recent years have seen a huge increase in research activity to fill this gap. The development of new drugs for diabetes and obesity must be founded upon a sound appreciation of the pathophysiology of these common disorders. The dual defects of insulin resistance and impaired insulin …
Translational Neuroscience offers a far-reaching and insightful series of perspectives on the effort to bring potentially revolutionary new classes of therapies to the clinic, thereby transforming the treatment of human nervous system disorders. Great advances in the fields of basic neuroscience, molecular biology, genomics, gene therapy, cell therapy, stem cell biology, information technology,…
This book covers wide areas of animal and human psychopharmacology with clinical utility in the treatment of psychiatric and neurological (e.g Alzheimer's disease) disorders. The main theme is to develop a new paradigm for drug discovery that questions the claim that animal models or assays fail adequately to predict Phase 3 clinical trials. A new paradigm is advocated that stresses the importa…
With fascinating, spectacularly beautiful images, the book piques readers’ curiosity about the diversity of visual organs. This book is the result of a dual approach – scientific as well as aesthetic. The compelling images are accompanied by an easy-to-read, understandable text, aimed at both scientists and the educated public, and generally anyone interested in the beauty of nature. Thanks…