This thesis examines the evidence for regulatory ubiquitination by focusing on A20. It provides an insightful and in-depth evaluation of the current literature by critically examining the evidence of K63-linked regulatory ubiquitination in regulating cell-signalling. It is also the first thesis to directly test the role of regulatory ubiquitination in NF-kB signaling in vivo. The case for regul…
What makes up a public, what governs dominant discourses, and in which ways can counterpublics be created through narrative? This edited collection brings together essays on affect and narrative theory with a focus on the topics of gender and sexuality. It explores the power of narrative in literature, film, art, performance, and mass media, the construction of subjectivities of gender and sexu…
This book summarizes the evidence from different African countries about the local impacts of climate change, and how farmers are coping with current climate risks. The different contributors show how agricultural systems in developing countries are affected by climate changes and how communities prepare and adapt to these changes.
Individual turnpike results are of great interest due to their numerous applications in engineering and in economic theory; in this book the study is focused on new results of turnpike phenomenon in linear optimal control problems. The book is intended for engineers as well as for mathematicians interested in the calculus of variations, optimal control and in applied functional analysis. Two…
This book explores some of the major turning points in the history of mathematics, ranging from ancient Greece to the present, demonstrating the drama that has often been a part of its evolution. Studying these breakthroughs, transitions, and revolutions, their stumbling-blocks and their triumphs, can help illuminate the importance of the history of mathematics for its teaching, learning, and …
This book provides an overview of the confluence of ideas in Turing’s era and work and examines the impact of his work on mathematical logic and theoretical computer science. It combines contributions by well-known scientists on the history and philosophy of computability theory as well as on generalised Turing computability. By looking at the roots and at the philosophical and technical infl…
This fourteenth volume of the series provides comprehensive, current information on the diagnosis, therapy and prognosis of brain tumors and spinal tumors. For the readers' convenience, contributions are organized into three categories of Pineal Tumors, Pituitary Tumors, and Spinal Tumors. Readers will find discussion of various aspects of a number of tumor types, including angiocentric glioma,…
This Brief provides a comprehensive overview of Trypanosoma cruzi, a parasite that is traditionally considered as exclusively vectorborne, but can be foodborne, and may lead to outbreaks of Chagas disease in consumers. The characteristics of Trypanosoma cruzi and the clinical effects of the disease are covered, including documented outbreaks, regional patterns, and epidemiology. The various tra…
Eszter Szép’s Comics and the Body is the first book to examine the roles of the body in both drawing and reading comics within a single framework. With an explicit emphasis on the ethical dimensions of bodily vulnerability, Szép takes her place at the forefront of scholars examining comics as embodied experiences, pushing this line of inquiry into bold new territory. Focusing on graphic aut…
Campus Medius explores and expands the possibilities of digital cartography in cultural and media studies. Simon Ganahl documents the development of the project from a historical case study to a mapping platform. Based on the question of what a media experience is, the concepts of the apparatus (dispositif) and the actor-network are translated into a data model. A time-space of twenty-four hour…