This volume is a comprehensive and rigorous exploration of intertwined issues surrounding the EU's democracy and legitimacy, written in the turbulent context of the financial crisis. The chapters are woven together under four interconnected thematic sections that examine: rapidly growing national euroscepticism; the Economic Monetary Union and its legitimacy; the future of EU integration; and d…
This book addresses and synthesizes recent basic, translational, and clinical research with the goal of understanding the mechanisms behind autism spectrum disorder (ASD) and how they lead to altered brain function and behavior. Bringing clarity to these mechanisms will lead to more effective therapies for the various heterogeneous pathologies that comprise ASD. Currently there are few, if any,…
This handbook covers established and advanced techniques for biomarker analysis, such as guidelines and strategies for assay validation methods; different mathematical models that are necessary in contemporary drug discovery and development; and evaluation of new cytometry methods. Expertly curated by two practicing professionals in drug development and biotherapeutics, individual chapters are …
This is the first English book that presents a professional analysis of the recent dynamic movement of the Chinese economy by focusing on the Yangtze River Delta region, which is the main engine of the Chinese economy. The impact of the international financial crisis on China’s economic development requires a change from the first wave of economic globalization oriented toward exports to the …
This book presents basic and extensive information on the physiological and pathological significance of the protein-modifying enzymes, transglutaminases, which are involved in multiple biological events by catalyzing a unique and important posttranslational modification reaction, cross-linking of proteins, and interacting with a large number of proteins inside and outside of cells. Although se…
There has been much attention paid to the idea of Smart Cities as researchers have sought to define and characterize the main aspects of the concept, including the role of creative industries in urban growth, the importance of social capital in urban development, and the role of urban sustainability. This book develops a critical view of the Smart City concept, the incentives and role of govern…
This volume focuses on modern computational and statistical tools for translational gene expression and regulation research to improve prognosis, diagnostics, prediction of severity, and therapies for human diseases. It introduces some of state of the art technologies as well as computational and statistical tools for translational bioinformatics in the areas of gene transcription and regulatio…
Nearly 30 years ago, a number of scientists working on the Enteric Nervous System (ENS) gathered at Flinders University, in Adelaide, Australia to discuss the advances and future of their research. It was a friendly and stimulating meeting, attended by most of the major players, in what was to become the discipline of ‘Neurogastroenterology'. In 2014, the main Australasian Neuroscience Soc…
This book reports on the first empirical validation of “AccuRate,” Australia’s national benchmark software tool for house energy ratings. The validation was conducted by the University of Tasmania in collaboration with Forest and Wood Products Australia, the Australian Government, the CSIRO and industry partners. The study presented here describes the results of graphical and statistical …
This book offers a detailed account of the recent Israeli-Greek rapprochement. For more than six decades, relations between Greece and Israel were characterized by suspicion, mutual recriminations and hostility. However, in 2009, Greek policy was unexpectedly overturned. This volume examines this new relationship in detail and explores its theoretical and regional consequences. The Introduction…