This book presents a common principle of actions of long noncoding RNAs (lncRNAs) from points of view at the atomic, molecular and cellular levels. At the atomic level, chemical studies of ribonucleic acids explain the chemical behavior of lncRNAs. Structural biological analysis of lncRNAs and its binding proteins also reveal the precise mechanisms of their actions. Molecular biological approac…
This volume focuses on the roles of long non-coding RNAs (lncRNAs) in contexts ranging from human cancers to cardiovascular disease and ageing. The role of lncRNAs in X-inactivation and those lncRNAs derived from pseudogenes, past retroelements integrated within the human genome, as well as the role these pseudogene-derived lncRNAs play in cancer development are discussed in detail. Further, th…
The Zicklin School of Business Financial Markets Series presents the insights emerging from a sequence of conferences hosted by the Zicklin School at Baruch College for industry professionals, regulators, and scholars. Much more than historical documents, the transcripts from the conferences are edited for clarity, perspective and context; material and comments from subsequent interviews with t…
This is the seventh book in a series of discussions about the great minds in the history and theory of finance. While the series addresses the contributions of scholars in our understanding of financial decisions and markets, this seventh book describes how econometrics developed and how its underlying assumptions created the underpinning of much of modern financial theory. The author shows tha…
This contributed volume contains the selected and thoroughly reviewed research papers presented at the conference on logistics management LM2015 in Braunschweig, Germany. The conference of the special interest group in logistics of the German Academic Association for Business Research (VHB) was held in conjunction with the special interest group on production of the VHB. Thus, the papers reflec…
This book will be of interest to anyone studying the calculus of variations who wants a deeper intuition for the techniques and ideas that are used, as well as historians of science and mathematics interested in the development and evolution of modern calculus and analysis.
This thesis presents an in-depth, high-resolution observational study on the very beginning of the formation process: the fragmentation of dense molecular clouds known as infrared dark clouds (IRDCs). Using the Submillimeter Array (SMA) and Very Large Array (VLA) radio interferometers, the author has discovered a common picture of hierarchical fragmentation that challenges some of the leading t…
This book examines the EU accession to the ECHR from a systemic perspective as well as from the specific perspective of the 2013 draft accession agreement negotiated between the relevant body of the Council of Europe and the EU Commission. It mainly follows a legal positivist approach to examining the nature and scope of obligations that will regulate the new relationship between EU law and Eur…
This book covers the identification and role of endogenous lung stem cells in health and disease, particularly the most recent advances. In addition, it discusses the rapidly growing field of stem cells and cell therapy as it relates to lung biology and disease as well as ex vivo lung bioengineering. Such approaches may provide novel therapeutic approaches for lung diseases. Human pluripotent s…
The purpose of this volume is to identify and analyze the mechanisms and processes through which concepts and institutions of transcultural phenomena gain and are given momentum. Applied to a range of cases, including examples drawn from ancient Greece and modern India, the early modern Portuguese presence in China and politics of elite-mass dynamics in the People’s Republic of China, the boo…