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The Smoothened Receptor in Cancer and Regenerative Medicine
Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemist…
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- ISBN/ISSN
- 978-3-319-19755-5
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Online Algorithms for the Portfolio Selection Problem
Robert Dochow mathematically derives a simplified classification structure of selected types of the portfolio selection problem. He proposes two new competitive online algorithms with risk management, which he evaluates analytically. The author empirically evaluates online algorithms by a comprehensive statistical analysis. Concrete results are that follow-the-loser algorithms show the most pro…
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- 1
- ISBN/ISSN
- 978-3-658-13528-7
- Collation
- XXVI, 185
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- -
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Decision support systems IV : information and knowledge management in decisio…
This book contains extended and revised versions of a set of selected papers from two events organized by the Euro Working Group on Decision Support Systems (EWG-DSS), which were held in Toulouse, France and Barcelona, Spain, in June and July 2014. Overall, 8 papers were accepted for publication in this edition after a rigorous review process through at least three internationally known experts…
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- ISBN/ISSN
- 9783319215365
- Collation
- ix, 101 pages
- Series Title
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- Call Number
- 001.4
Decision support systems V -- big data analytics for decision making : first …
This book constitutes the refereed proceedings of the First International Conference on Decision Support Systems Technology, ICDSST 2015, held in Belgrade, Serbia, in May 2015. The theme of the event was "Big Data Analytics for Decision-Making" and it was organized by the EURO (Association of European Operational Research Societies) working group of Decision Support Systems (EWG-DSS). The eight…
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- ISBN/ISSN
- 9783319185330
- Collation
- xv, 111 pages
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- Call Number
- 001.4
The Role of Microenvironment in the Control of Tumor Angiogenesis
This work describes the importance of tumor microenvironment in favouring tumor progression and angiogenesis. Under physiological conditions, angiogenesis is dependent on the balance of positive and negative angiogenic modulators within the vascular microenvironment and requires the functional activities of a number of molecules, including angiogenic factors, extracellular matrix proteins, a…
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- ISBN/ISSN
- 978-3-319-27820-9
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Immunotherapy of Melanoma
This book focusses on the different types of immunotherapeutics that are currently being used and developed for the treatment of melanoma. In recent years, immunotherapy has revolutionized the treatment of metastatic melanoma and other types of cancer. Discussing treatment options for melanoma and the success of immunotherapy along with the challenges of immunotherapy, this book covers epide…
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- ISBN/ISSN
- 978-3-319-48065-7
- Collation
- XI, 434
- Series Title
- -
- Call Number
- 6169 ROT i
Nutrition, Exercise and Epigenetics: Ageing Interventions
This book focuses on the three most important aspects of ageing research: nutrition, physical exercise and epigenetics. The contributors discuss ways that age-related epigenetic imprints such as DNA methylation and histone acetylation are modified by these two interventions. The emphasis on epigenetics helps to illuminate the underlying mechanisms of anti-ageing interventions, as ageing and dis…
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- 1
- ISBN/ISSN
- 978-3-319-14829-8
- Collation
- VIII, 278
- Series Title
- Healthy Ageing and Longevity
- Call Number
- -
Nutrigenomics
The fascinating area of Nutrigenomics describes this daily communication between diet, food and nutrients, their metabolites and our genome. This book describes how nutrition shapes human evolution and demonstrates its consequences for our susceptibility to diseases, such as diabetes and atherosclerosis. Inappropriate diet can yield stress for our cells, tissues and organs and then it is often …
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- 1
- ISBN/ISSN
- 978-3-319-30413-7
- Collation
- XXI, 222
- Series Title
- -
- Call Number
- -
Numerical Optimization with Computational Errors
This book studies the approximate solutions of optimization problems in the presence of computational errors. A number of results are presented on the convergence behavior of algorithms in a Hilbert space; these algorithms are examined taking into account computational errors. The author illustrates that algorithms generate a good approximate solution, if computational errors are bounded from a…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-30920-0
- Collation
- IX, 304
- Series Title
- Springer Optimization and Its Applications
- Call Number
- -
Novel Chemical Tools to Study Ion Channel Biology
This volume describes chemical approaches to assess ion channel structure, function and pharmacology. Topics discussed include the use of engineered ionizable side chains to obtain information on permeation pathways and the local environment; the modification of engineered cysteine side chains, including cysteine scanning mutagenesis and the attachment of fluorescent probes and bio-reactive tet…
- Edition
- 1
- ISBN/ISSN
- 978-1-4939-2844-6
- Collation
- VIII, 154
- Series Title
- Advances in Experimental Medicine and Biology
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- -
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