This book presents a common principle of actions of long noncoding RNAs (lncRNAs) from points of view at the atomic, molecular and cellular levels. At the atomic level, chemical studies of ribonucleic acids explain the chemical behavior of lncRNAs. Structural biological analysis of lncRNAs and its binding proteins also reveal the precise mechanisms of their actions. Molecular biological approac…
This volume focuses on the roles of long non-coding RNAs (lncRNAs) in contexts ranging from human cancers to cardiovascular disease and ageing. The role of lncRNAs in X-inactivation and those lncRNAs derived from pseudogenes, past retroelements integrated within the human genome, as well as the role these pseudogene-derived lncRNAs play in cancer development are discussed in detail. Further, th…
This book constitutes thoroughly revised, selected papers of the proceedings of the 6th International Workshop on Collaborative Agents Research and Development, CARE 2015 and the Second International Workshop on Multi-agent Foundations of Social Computing, MFSC 2015, held in Istanbul, Turkey, on May 4, 2015. Both Workshops were held in conjunction with AAMAS 2015. The 5 revised full papers o…
The first section explores genome-wide association studies, the extension of this method to less accessible phenotypes and the arrival of next-generation sequencing. A further section goes beyond genetics to illustrate how other data sources can help interpret genetic data, such as leveraging population diversity, the correlation of genetic associations with physiological measurements, gene exp…
This Edited Volume contains a selection of refereed and revised papers originally presented at the second International Symposium on Signal Processing and Intelligent Recognition Systems (SIRS-2015), December 16-19, 2015, Trivandrum, India. The program committee received 175 submissions. Each paper was peer reviewed by at least three or more independent referees of the program committee and the…
This book constitutes the refereed proceedings of the 9th Asia-Pacific Services Computing Conference, APSCC 2015, held in Bangkok, Thailand, in December 2015.The 17 revised full papers and 6 short papers presented were carefully reviewed and selected from numerous submissions. The papers cover a wide range of topics in services computing, web services, cloud computing, security in services, and…
This book contains the articles from the international conference 11th Workshop on Self-Organizing Maps 2016 (WSOM 2016), held at Rice University in Houston, Texas, 6-8 January 2016. WSOM is a biennial international conference series starting with WSOM'97 in Helsinki, Finland, under the guidance and direction of Professor Tuevo Kohonen (Emeritus Professor, Academy of Finland). WSOM brings toget…
This book gives an in-depth overview on nuclear structure and function. It clearly shows that the epigenome and the three-dimensional organization of the nucleus are not independent properties. The intimate relationship between the location and the epigenetic modifications of gene loci is highlighted. Finally, it shows that the complex three-dimensional organization of the nucleus is not just o…
This book covers a wide range of local image descriptors, from the classical ones to the state of the art, as well as the burgeoning research topics on this area. The goal of this effort is to let readers know what are the most popular and useful methods in the current, what are the advantages and the disadvantages of these methods, which kind of methods is best suitable for their problems or a…
This book explores how dynamic changes in products' sensory features can be used to convey information to the user in an effective and engaging way. The aim is to supply the reader with a clear understanding of an important emerging area of research and practice in product design, referred to as dynamic products, which is opening up new possibilities for the integration of product design with d…