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The Role of Microenvironment in the Control of Tumor Angiogenesis
This work describes the importance of tumor microenvironment in favouring tumor progression and angiogenesis. Under physiological conditions, angiogenesis is dependent on the balance of positive and negative angiogenic modulators within the vascular microenvironment and requires the functional activities of a number of molecules, including angiogenic factors, extracellular matrix proteins, a…
- Edition
- -
- ISBN/ISSN
- 978-3-319-27820-9
- Collation
- -
- Series Title
- -
- Call Number
- -
Immunotherapy of Melanoma
This book focusses on the different types of immunotherapeutics that are currently being used and developed for the treatment of melanoma. In recent years, immunotherapy has revolutionized the treatment of metastatic melanoma and other types of cancer. Discussing treatment options for melanoma and the success of immunotherapy along with the challenges of immunotherapy, this book covers epide…
- Edition
- -
- ISBN/ISSN
- 978-3-319-48065-7
- Collation
- XI, 434
- Series Title
- -
- Call Number
- 6169 ROT i
Nutrition, Exercise and Epigenetics: Ageing Interventions
This book focuses on the three most important aspects of ageing research: nutrition, physical exercise and epigenetics. The contributors discuss ways that age-related epigenetic imprints such as DNA methylation and histone acetylation are modified by these two interventions. The emphasis on epigenetics helps to illuminate the underlying mechanisms of anti-ageing interventions, as ageing and dis…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-14829-8
- Collation
- VIII, 278
- Series Title
- Healthy Ageing and Longevity
- Call Number
- -
Nutrigenomics
The fascinating area of Nutrigenomics describes this daily communication between diet, food and nutrients, their metabolites and our genome. This book describes how nutrition shapes human evolution and demonstrates its consequences for our susceptibility to diseases, such as diabetes and atherosclerosis. Inappropriate diet can yield stress for our cells, tissues and organs and then it is often …
- Edition
- 1
- ISBN/ISSN
- 978-3-319-30413-7
- Collation
- XXI, 222
- Series Title
- -
- Call Number
- -
Numerical Optimization with Computational Errors
This book studies the approximate solutions of optimization problems in the presence of computational errors. A number of results are presented on the convergence behavior of algorithms in a Hilbert space; these algorithms are examined taking into account computational errors. The author illustrates that algorithms generate a good approximate solution, if computational errors are bounded from a…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-30920-0
- Collation
- IX, 304
- Series Title
- Springer Optimization and Its Applications
- Call Number
- -
Novel Chemical Tools to Study Ion Channel Biology
This volume describes chemical approaches to assess ion channel structure, function and pharmacology. Topics discussed include the use of engineered ionizable side chains to obtain information on permeation pathways and the local environment; the modification of engineered cysteine side chains, including cysteine scanning mutagenesis and the attachment of fluorescent probes and bio-reactive tet…
- Edition
- 1
- ISBN/ISSN
- 978-1-4939-2844-6
- Collation
- VIII, 154
- Series Title
- Advances in Experimental Medicine and Biology
- Call Number
- -
Citizen Science : Innovation in Open Science, Society and Policy
Citizen science, the active participation of the public in scientific research projects, is a rapidly expanding field in open science and open innovation. It provides an integrated model of public knowledge production and engagement with science. As a growing worldwide phenomenon, it is invigorated by evolving new technologies that connect people easily and effectively with the scientific commu…
- Edition
- -
- ISBN/ISSN
- 9781787352339
- Collation
- -
- Series Title
- -
- Call Number
- 320 HEC c
Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy: New Perspectives an…
This book discusses properties of apoptosis and other cell death modalities in cancer pathogenesis and treatment. Its nine chapters discuss modulation of anti-tumor inflammatory and immune responses, effects on the tumor microenvironment, to strategies for improving pro-apoptotic therapies, mechanisms and implications for disease pathogenesis, axl and mer receptor tyrosine kinases, immunogenic …
- Edition
- Ed. 1
- ISBN/ISSN
- 978-3-319-39406-0
- Collation
- XVII, 247
- Series Title
- Advances in Experimental Medicine and Biology
- Call Number
- 616.994 APO a
Design science research : a method for science and technology advancement
Consolidating existing knowledge in Design Science, this book proposes a new research method to aid the exploration of design and problem solving within business, science and technology. It seeks to overcome a dichotomy that exists in the field between theory and practice to enable researches to find solutions to problems, rather than focusing on the explanation and exploration of the problems …
- Edition
- -
- ISBN/ISSN
- 9783319073736
- Collation
- xviii, 161 pages : illustrations ; 25 cm
- Series Title
- -
- Call Number
- 001.42
The Hsp60 Chaperonin
In this unique overview of the Hsp60 chaperonin, Peter Bross addresses molecular biologists, medical research scientists and individuals interested in molecular or general biology. First, Bross discusses the basics of the Hsp60 chaperonin in terms of its structure and the molecular mechanisms determining its function. Second, the author highlights the multiple roles of Hsp60 for cellular system…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-26088-4
- Collation
- XV, 85,15 b/w illustrations, 4 illustrations in colour
- Series Title
- SpringerBriefs in Molecular Science
- Call Number
- -
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