Magnesium is universally recognized as an essential nutrient for human life and health. Indeed, magnesium plays an important physiologic role in every organ of the human body. Disturbances of Mg homeostasis have been implicated in the pathophysiology of several diseases, and Mg supplementation has been evaluated in numerous large-scale clinical trials. The World Health Organization has listed m…
This book covers a wide array of hematologic problems commonly encountered in the daily practice of critical care and emergency medicine. Unfortunately, the symptoms and signs associated with underlying hematologic disorders are frequently rather unspecific and confounding; furthermore, the clinical course of patients admitted to intensive care units with such disorders can be fulminant, warran…
This book represents the first comprehensive textbook devoted to the standard of care, current guidelines and innovations in the field of mesenteric vascular disease. The book reviews imaging modalities, diagnostic work up, physiologic tests, traditional open surgical techniques and novel endovascular approaches. Technical aspects of both open surgical and endovascular techniques are provided b…
Appropriate mathematical tools and methodologies are critical for ensuring robust and reliable computational model predictions based on medical and healthcare data in the era of the digital health revolution (Duggal et al., 2018). Patient-specific approaches are being increasingly pursued, with simulations benchmarked by clinical data (e.g., brain activity recordings; Breakspear, 2017) obtain…
Cancer care delivery refers to the multiple layers of the health care system that interact to affect outcomes for patients with cancer and the quality of that care. The factors included in the care delivery system that potentially alter outcomes include social dynamics, financing systems, organizational structures and processes, health technologies, provider and individual behaviors. Because wo…
This book explores the nature of pregnancy and metabolic syndrome as proinflammatory conditions and explains how pregnancy provides a window of opportunity for preventing the lifelong complications of metabolic syndrome, during which key risk factors can be identified and beneficial dietary changes can be implemented. The book’s opening sections discuss inflammation in the context of pregn…
This book develops and analyses computational wear simulations of the total ankle replacement for the stance phase of gait cycle. The emphasis is put on the relevant design parameters. The book presents a model consisting of three components; tibial, bearing and talar representing their physiological functions.
This book is exceptional in being devoted solely to vasovagal syncope (VVS), the most frequent cause of transient loss of consciousness in the general population. All aspects of VVS are covered, including epidemiology, pathophysiology, diagnosis and differential diagnosis, prognosis, therapy and implications for particular activities such as work, driving and physical activity. The context for …
The carotid body (CB) is the main arterial chemoreceptor in charge of adjusting ventilatory and cardiovascular function during changes in arterial blood gases. Regardless this essential function, the CB has been implicated in the sensing of other physiological signals such as changes in blood flow and glucose levels. More important, malfunction of the CB chemoreceptors has been associated with …
This book focuses on the rapidly developing and promising novel applications of Dual Energy CT (DECT) in cardiovascular medicine. Although developed many years ago, DECT represents the newest significant advancement in the field of computed tomography, the clinical utility of which has recently expanded as many new applications have been developed. In the field of cardiovascular medicine, DECT …