This book provides an up-to-date review of recently identified natural anti-tumor compounds from various natural origins including plants, fungi, endophytic fungi and marine organisms. It also includes discussion of new areas such as biotechnology and nanoparticles. Chapters explain the challenges and developments in anti-cancer drug discovery approaches, traditional remedies for prevention an…
This volume gives an overview of state of the art technologies and future developments in the field of preclinical pharmaceutical research. A balanced mix of experts from academia and industry give insight in selected new developments in the drug discovery pathway. The topics cover the different parts of the drug discovery process, starting with new developments in the target identification and…
The discovery of monolayer graphene led to a Nobel Prize in Physics being awarded in 2010. This has stimulated further research on a wide variety of two-dimensional (2D) layered materials. The coupling of metallic graphene, semiconducting 2D transition metal dichalcogenides (TMDCs) and black phosphorus have attracted a tremendous amount of interest in new electronic and optoelectronic applicati…
This book provides a detailed account of the most recent developments, challenges and solutions to seamlessly advance and launch a lyophilized biologics or vaccine product, based on diverse modalities, ranging from antibodies (e.g., monoclonal, fused), complex biologics (e.g., antibody drug conjugate, PEGylated proteins), and vaccines (e.g., recombinant-protein based). The authors adeptly guide…
“Infogest” (Improving Health Properties of Food by Sharing our Knowledge on the Digestive Process) is an EU COST action/network in the domain of Food and Agriculture that will last for 4 years from April 4, 2011. Infogest aims at building an open international network of institutes undertaking multidisciplinary basic research on food digestion gathering scientists from different origins (fo…
The North is changing at an unprecedented rate as industrial development and the climate crisis disrupt not only the environment but also long-standing relationships to the land and traditional means of livelihood. Memory and Landscape: Indigenous Responses to a Changing North explores the ways in which Indigenous peoples in the Arctic have adapted to challenging circumstances, including past c…
While contemporaries and historians alike hailed the establishment of Buffalo National Park in Wainwright, Alberta as a wildlife saving effort, the political climate of the early twentieth century worked against its efforts to stem the decline of the plains buffalo in North America. However, the branch charged with operating the park, the Canadian Parks Branch, was never sufficiently funded and…
In the mid-1960s as a young high school student John Brumley visited Lookout Cave for the first time and knew immediately that the site was exceptional. The cave, located in north central Montana, was initially discovered in 1920 but it wasn’t until 1969 that a field crew from the University of Montana excavated a large portion of the remote site. The materials recovered in that excavation re…
Light from Ancient Campfires is the first book in twenty years to gather together a comprehensive prehistoric archaeological record of the Northern Plains First Nations. In this important examination of the region’s earliest inhabitants, author Trevor Peck reviews the many changes of interpretation that have occurred in relevant literature published during the last two decades. Beginning with…
Ecology & Wonder makes several remarkable claims: The greatest cultural achievement in the Western Canadian mountain region may be what has been preserved, not what has been developed. Protecting the spine of the Rocky Mountains will preserve crucial ecological functions. Because the process of ecosystem diminishment and species loss has been slowed, an ecological thermostat has been kept alive…