The role of vitamin A in living organisms has been known throughout human history. In the last 100 years, the biochemical nature of vitamin A and its active derivative, retinoic acid, its physiological impact on growth processes, and the essential details of its mechanism of action have been revealed by investigations carried out by researchers using vertebrate and more recently invertebrate mo…
This multi-disciplinary, multi-jurisdictional collection offers the first ever full-scale analysis of legal fictions. Its focus is on fictions in legal practice, examining and evaluating their roles in a variety of different areas of practice (e.g. in Tort Law, Criminal Law and Intellectual Property Law) and in different times and places (e.g. in Roman Law, Rabbinic Law and the Common Law). The…
Interfaces are created to separate two distinct phases in a situation in which phase coexistence occurs. This book discusses randomly fluctuating interfaces in several different settings and from several points of view: discrete/continuum, microscopic/macroscopic, and static/dynamic theories. The following four topics in particular are dealt with in the book. Assuming that the interface is rep…
s text presents a wide-ranging and rigorous overview of nearest neighbor methods, one of the most important paradigms in machine learning. Now in one self-contained volume, this book systematically covers key statistical, probabilistic, combinatorial and geometric ideas for understanding, analyzing and developing nearest neighbor methods. Gérard Biau is a professor at Université Pierre et Ma…
Since its establishment in 1965, Business Economics has been an essential resource for those who use economics in the workplace. Its consistent intent has been to distinguish itself from academic journals by focusing on what is useful to practitioners of economics in their everyday work, and it has risen to become the leading forum for debating solutions to critical business problems, analyzing…
This volume gathers the content of the courses held at the Third IDPASC School, which took place in San Martiño Pinario, Hospederia and Seminario Maior, in the city of Santiago de Compostela, Galiza, Spain, from January 21st to February 2nd, 2013. This school is the annual joint program of the International Doctorate Network in Particle Physics, Astrophysics, and Cosmology (IDPASC). Th…
This book mainly serves as an elementary, self-contained introduction to several important aspects of the theory of global solutions to initial value problems for nonlinear evolution equations. The book employs the classical method of continuation of local solutions with the help of a priori estimates obtained for small data. The existence and uniqueness of small, smooth solutions that are defi…
An overview of all the available literature on the various aspects of the regulation of the cardiovascular system`s function and physiology by the adrenergic neurohormonal system, i.e. the catecholamines norepinephrine and epinephrine. Although there are several books describing the adrenergic system`s biology, physiology and pharmacology, and also several excellent books on cardiovascular phys…
How can a place be built and managed so that it is safe for people to live? Ironically, many governments and citizens keep on asking the same question after every new disaster. Why, even with high levels of investment in increasing government’s capacity to manage disasters, do the impacts of disasters continue to increase? What can the governments do differently? What is the role of local com…
These lecture notes aim at providing a purely analytical and accessible proof of the Callias index formula. In various branches of mathematics (particularly, linear and nonlinear partial differential operators, singular integral operators, etc.) and theoretical physics (e.g., nonrelativistic and relativistic quantum mechanics, condensed matter physics, and quantum field theory), there is much i…