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Non-coding RNAs in Colorectal Cancer
This is the first book to provide a broad framework for obtaining an in depth understanding of the state-of-the-art knowledge on abnormalities of non-coding RNAs found to be associated with colorectal cancer pathogenesis. Readers will discover possible mechanisms underlying the substantial roles played by non-coding RNAs in molecular hallmarks of colorectal cancer.This work further provides the…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-42057-8
- Collation
- VIII, 252
- Series Title
- Advances in Experimental Medicine and Biology
- Call Number
- -
Nitric Oxide and Cancer: Pathogenesis and Therapy
Advances in Nitric Oxide and Cancer is a volume that serves to give the latest research on nitric oxide (NO) and cancer. More specifically, the volume reviews significant advances in the application of NO-mediated drugs. The volume explores nitric oxide and its relationship to cancer spanning from its roles in the pathogenesis, prognosis, gene and protein modifications, regulation of resistance…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-35259-6
- Collation
- XXIII, 308
- Series Title
- -
- Call Number
- -
Railway Infrastructure Security
This comprehensive monograph addresses crucial issues in the protection of railway systems, with the objective of enhancing the understanding of railway infrastructure security. Based on analyses by academics, technology providers and railway operators, it explains how to assess terrorist and criminal threats, design countermeasures, and implement effective security strategies. In so doing, it …
- Edition
- -
- ISBN/ISSN
- 978-3-319-04426-2
- Collation
- -
- Series Title
- -
- Call Number
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Optimizing Liner Shipping Fleet Repositioning Plans
This monograph addresses several critical problems to the operations of shipping lines and ports, and provides algorithms and mathematical models for use by shipping lines and port authorities for decision support. One of these problems is the repositioning of container ships in a liner shipping network in order to adjust the network to seasonal shifts in demand or changes in the world economy.…
- Edition
- -
- ISBN/ISSN
- 978-3-319-17665-9
- Collation
- -
- Series Title
- -
- Call Number
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Optimized Packings with Applications
This volume presents a selection of case studies that address a substantial range of optimized object packings (OOP) and their applications. The contributing authors are well-recognized researchers and practitioners. The mathematical modelling and numerical solution aspects of each application case study are presented in sufficient detail. A broad range of OOP problems are discussed: these incl…
- Edition
- -
- ISBN/ISSN
- 978-3-319-18899-7
- Collation
- -
- Series Title
- -
- Call Number
- -
Optimization, Control, and Applications in the Information Age In Honor of P…
Recent developments in theory, algorithms, and applications in optimization and control are discussed in this proceedings, based on selected talks from the ‘Optimization Control and Applications in the Information Age’ conference, organized in honor of Panos Pardalos’s 60th birthday. This volume contains numerous applications to optimal decision making in energy production and fuel manage…
- Edition
- -
- ISBN/ISSN
- 978-3-319-18567-5
- Collation
- -
- Series Title
- -
- Call Number
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Optimization of Stochastic Discrete Systems and Control on Complex Networks …
This book presents the latest findings on stochastic dynamic programming models and on solving optimal control problems in networks. It includes the authors’ new findings on determining the optimal solution of discrete optimal control problems in networks and on solving game variants of Markov decision problems in the context of computational networks. First, the book studies the finite state…
- Edition
- -
- ISBN/ISSN
- 978-3-319-11833-8
- Collation
- -
- Series Title
- -
- Call Number
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Optimization of Polynomials in Non-Commuting Variables
This book presents recent results on positivity and optimization of polynomials in non-commuting variables. Researchers in non-commutative algebraic geometry, control theory, system engineering, optimization, quantum physics and information science will find the unified notation and mixture of algebraic geometry and mathematical programming useful. Theoretical results are matched with algorithm…
- Edition
- -
- ISBN/ISSN
- 978-3-319-33338-0
- Collation
- -
- Series Title
- -
- Call Number
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Optimization of Pharmaceutical R&D Programs and Portfolios Design and Invest…
Very little has been published on optimization of pharmaceutical portfolios. Moreover, most of published literature is coming from the commercial side, where probability of technical success (PoS) is treated as fixed, and not as a consequence of development strategy or design. In this book there is a strong focus on impact of study design on PoS and ultimately on the value of portfolio. Design …
- Edition
- -
- ISBN/ISSN
- 978-3-319-09075-7
- Collation
- -
- Series Title
- -
- Call Number
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Optimization of Integrated Supply Chain Planning under Multiple Uncertainty
The subject of this book is supply chain logistics planning optimization under multiple uncertainties, the key issue in supply chain management. Focusing on the strategic-alliance three-level supply chain, the model of supply chain logistics planning was established in terms of the market prices and the market requirements as random variables of manufactured goods with random expected value…
- Edition
- -
- ISBN/ISSN
- 978-3-662-47250-7
- Collation
- -
- Series Title
- -
- Call Number
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