This text provides expert instruction on the techniques currently employed for the surgical treatment of glaucomatous disease, covering both the host of novel microinvasive devices for treatment of milder stages and the refined strategies that enhance success rates in patients with advanced disease. The critical steps in each procedure are clearly described with the aid of many high-quality ill…
Lasso peptides form a growing family of fascinating ribosomally-synthesized and post-translationally modified peptides produced by bacteria. They contain 15 to 24 residues and share a unique interlocked topology that involves an N-terminal 7 to 9-residue macrolactam ring where the C-terminal tail is threaded and irreversibly trapped. The ring results from the condensation of the N-terminal amin…
aser measurement technology has evolved in the last years in a versatile and reflationary way. Today, its methods are indispensable for research and development activities as well as for production technology. Every physicist and engineer should therefore gain a working knowledge of laser measurement technology. This book closes the gap of existing textbooks. It introduces in a comprehensible …
This work details an application of collinear resonance ionization spectroscopy for the separation of short-lived isomeric states and their subsequent study with decay spectroscopy. It reports the successful construction of a novel decay spectroscopy apparatus that can operate at pressures below 1 x 10^-9 mbar. The method is demonstrated by separating the nuclear ground and isomeric states of 2…
This book entitled “Laser Additive Manufacturing of High-Performance Materials” covers the specific aspects of laser additive manufacturing of high-performance new materials components based on an unconventional materials incremental manufacturing philosophy, in terms of materials design and preparation, process control and optimization and theories of physical and chemical metallurgy. This…
Teaching about technology, at all levels of education, can only be done properly when those who teach have a clear idea about what it is that they teach. In other words: they should be able to give an appropriate answer to the question: what is technology? The question of the nature of technology is explored in the philosophy of technology, making this a highly relevant discipline for those who…
The book expresses the conviction that the art of creating tools – Greek techne – changes its character together with the change of civilization epochs and co-determines such changes. This does not mean that tools typical for a civilization epoch determine it completely, but they change our way of perceiving and interpreting the world. There might have been many such epochs in the history o…
T-type calcium channels are prevalent in every organ of the body, and are believed to play a part in a variety of physiological processes, including contraction, shape change, secretion, endo- and exocytosis, cell proliferation and differentiation, modulation of enzyme function, and cell cycle progression. As such, research on the roles of these channels in a wide range of diseases has attracte…
This book contributes to making urban rail transport fast, punctual and energy-efficient –significant factors in the importance of public transportation systems to economic, environmental and social requirements at both municipal and national levels. It proposes new methods for shortening passenger travel times and for reducing energy consumption, addressing two major topics: (1) train traje…
This book primarily addresses the optimality aspects of covariate designs. A covariate model is a combination of ANOVA and regression models. Optimal estimation of the parameters of the model using a suitable choice of designs is of great importance; as such choices allow experimenters to extract maximum information for the unknown model parameters. The main emphasis of this monograph is to sta…