Genetics of Diabetes Mellitus is intended to be a resource for both researchers in the field as well as endocrinologists, diabetologists, and geneticists who seek to learn more about this rapidly changing and important field. The text contains chapters from experts in the area who review aspects of the genetics of both type 1 and 2 diabetes mellitus as well as various syndromic forms of diabete…
This title will be presented as highly practical information on pharmaceutical options in pulmonary hypertension, written in a quick-access, no-nonsense format. The emphasis will be on a just-the-facts clinical approach, heavy on tabular material, light on dense prose. The involvement of the ISCP will ensure that the best quality contributors will be involved and establish a consistent appro…
Recent research cited above has documented that QRS/T angle and other novel repolarization measures of deviant repolarization are potent predictors of cardiac morbidity and mortality over and above the traditional risk factors such as old ECG-MI, ECG-LVH or QT prolongation. A novel ECG model of repolarization based on electrophysiological considerations developed by the author has been the corn…
This book provides an up-to-date and comprehensive overview of the etiology, diagnosis and treatment of conditions affecting the structure and function of the right heart, comprising the right atrium, right ventricle, tricuspid valve and pulmonary circulation. Anatomy and physiology of the right heart, etiology and role of imaging of right heart failure, as well as treatment options, from pharm…
Thrombolytic therapy is finally starting to reach patients in a variety of settings all over the world. Formerly in the domain of sub-specialists, thrombolytic therapy now rests in the realm of Emergency Medicine, Intensive Care, Vascular, and Neuro hospital Medicine physicians. Increasingly, non-neurologists use thrombolytic therapy. This is a significant advancement since the 2nd edition to T…
This book provides an up-to-date review of the use of thrombolytic therapy in the treatment of acute pulmonary embolism. It discusses the mechanisms of thrombosis; pharmacokinetics and pharmacodynamics of the most commonly used fibrinolytics; evidence-based results from multicenter control trials in which thrombolytic treatment was administered; criteria by which pulmonary embolism patients req…
Three-dimensional echocardiography is the most recent fundamental advancement in echocardiography with a strong impact on almost all clinical and research applications of echocardiography. After a very successful 1st edition, this book presents the fully revised 2nd edition. Accounting for the marked progress of real-time 3D echocardiography since the 1st edition it covers all clinically imp…
This book is designed for clinical cardiologists and other physicians working with cardiac patients, where specific specialized teams of cardio-oncologists are not available and who are called to perform a clinical consultation to evaluate both the cardiac condition and the eligibility for chemotherapy or radiotherapy treatment, and to evaluate if a cancer treatment produces toxic effects on a …
This comprehensive book provides not only the stages in the development of this unique and specialized field but also updates on the current state of research and development of apolipoprotein mimetics as therapeutic modalities for various lipid-mediated disorders. The book consists of 11 chapters all written by leading scientists from well-reputed laboratories in the USA. After an introduction…
With the advent of less invasive treatments for aortic stenosis including percutaneous and apical replacement, more patients are being offered this technology. As such, determining the true severity of aortic stenosis is becoming paramount. Many clinical scenarios occur where the area and gradient estimates of severity do not match. This book will present case by case examples of different pa…