This work describes the current knowledge of biochemical mechanisms regulating initiation of DNA replication in Escherichia coli, which focuses on the control of activity of the DnaA protein. Examples of direct linkages between DNA replication and other cellular processes are provided. In addition, similarities of the mechanisms of regulation of DNA replication operating in prokaryotic and euka…
This book is a comprehensive review of the detailed molecular mechanisms of and functional crosstalk among the replication, recombination, and repair of DNA (collectively called the "3Rs") and the related processes, with special consciousness of their biological and clinical consequences. The 3Rs are fundamental molecular mechanisms for organisms to maintain and sometimes intentionally alter ge…
Diperkirakan bahwa produksi pertanian harus digandakan pada tahun 2050 untuk memenuhi perkiraan permintaan populasi dunia yang terus bertambah. Pencapaian tujuan ini merupakan tantangan serius bagi pemulia tanaman karena laju pertumbuhan produksi pertanian saat ini sebesar 1,3 % per tahun berada di bawah laju pertumbuhan populasi. Di masa lalu, kemajuan penelitian telah dibuat dalam pengembanga…
Dalam beberapa tahun terakhir, pemuliaan tanaman telah mengalami revolusi. Karena pengurangan biaya genotipe dan polimorfisme nukleotida tunggal, dimungkinkan untuk memperoleh sejumlah besar data genotipe dalam waktu singkat. Banjir informasi genom ini telah memicu pengembangan strategi baru untuk integrasi informasi molekuler dalam program pemuliaan. Namun, masih diperlukan data fenotipik yang…
DNA (deoxyribose nucleic acid) is extremely important. All living things have DNA, or in the case of some viruses they have RNA instead. In eukaryotes, it is found within the nucleus and is arranged into chromosomes. DNA determines the characteristics of an organism. Specific codes of DNA are called genes. DNA is made up of nucleotides. Nucleotides are repeating units, that are made up…
In molecular biology, DNA replication is the biological process of producing two identical replicas of DNA from one original DNA molecule. This process occurs in all living organisms and is the basis for biological inheritance. DNA is made up of a double helix of two complementary strands. During replication, these strands are separated. Each strand of the original DNA molecule then serves as a…