This book examines in detail the current treatment options for first-line, relapsed, and refractory Hodgkin lymphoma and the management appropriate in special clinical circumstances, including in the elderly, pregnant women, and those with lymphocyte-predominant disease. Careful attention is devoted to the emerging individually tailored treatment strategies that are especially appealing given t…
This volume presents the MD Anderson experience in providing care and services to the rapidly growing population of cancer survivors, which is currently estimated to be 12 million in the United States and more than 25 million worldwide. As cancer survival rates have increased, it has slowly become clear that the challenges faced by people with cancer do not end with treatment but simply change.…
What should you do when you have restricted resources? Written by the most prominent experts from the North and the South countries, this book offers a unique complement to classical hematology and oncology textbooks focusing on specific issues concerning cancers in tropical areas. It presents a thorough review of the specific biological, clinical and therapeutic characteristics of cancers in t…
Coagulation testing is the basis for the diagnosis of bleeding and thrombotic disorders, as well as the mainstay of anticoagulant monitoring and management. This handbook provides practical information and guidance on topics relevant to directing a coagulation laboratory, filling a void in the literature. Since the first edition, all chapters have been updated and an entirely new chapter is inc…
Due to a high incidence of anemia, critically ill patients are frequently transfused, with up to 40% of patients receiving a transfusion during their stay in the Intensive Care Unit. It has become increasingly clear that there is an association between transfusion and adverse outcomes, underlining the need for a careful assessment of the risks and benefits of a blood transfusion. In the last de…
This comprehensive volume discusses the protease ADAMTS13, summarizing the current status of basic and clinical research. The nine authoritative chapters begin with a historical perspective followed by exploration of the biochemistry and structure-function relationships of ADAMTS13 as well as its normal function in hemostasis (cleavage of von Willebrand factor). Emerging research themes for ADA…
This book surveys healthy and diseased vascular systems in a multitude of model organisms and systems. It explores a plethora of functions, characteristics, and pathologies of the vascular system such as angiogenesis, fibroblast growth factor signaling, lymphangiogenesis, junctional signaling, the extracellular matrix, vascular permeability, leukocyte extravasation, axon guidance factors, the a…
This book gives a comprehensive insight into platelet biogenesis, platelet signal transduction, involvement of platelets in disease, the use of diverse animal models for platelet research and future perspectives in regard to platelet production and gene therapy. Being written by international experts, the book is a concise state-of-the art work in the field of platelet biogenesis, biology and r…
In this ground-breaking account of the political economy and cultural meaning of blood in contemporary India, Jacob Copeman and Dwaipayan Banerjee examine how the giving and receiving of blood has shaped social and political life. Hematologies traces how the substance congeals political ideologies, biomedical rationalities, and activist practices.Using examples from anti-colonial appeals to blo…
In this ground-breaking account of the political economy and cultural meaning of blood in contemporary India, Jacob Copeman and Dwaipayan Banerjee examine how the giving and receiving of blood has shaped social and political life. Hematologies traces how the substance congeals political ideologies, biomedical rationalities, and activist practices.Using examples from anti-colonial appeals to blo…