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Therapeutic Perspectives in Type-1 Diabetes
This book provides critical insights into and appraisals of recent breakthroughs in type 1 diabetes modulation, with a particular emphasis on the potential impact of current prevention and treatment strategies. It also discusses recent successes and failures in clinical trials. Presenting an comprehensive overview of the disease, it is especially useful for newcomers in the field. It also inclu…
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- 978-981-10-0602-9
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The Smoothened Receptor in Cancer and Regenerative Medicine
Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemist…
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- 978-3-319-19755-5
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Hyperbranched Polydendrons : A New Macromolecular Architecture
This thesis outlines the first synthesis of a new complex branched polymer architecture that aims to combine the benefits of dendrimers with the simplicity of conventional polymerisation. There is no other available literature on these remarkable materials, dubbed hyperbranched polydendrons, due to their novelty. The new materials were shown to have very high molecular weights (>1,000,000 g/mol…
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- 978-3-319-18752-5
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- XXII, 260
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- 615.19 HYP
Asymmetric Synthesis of Bioactive Lactones and the Development of a Catalytic…
This thesis addresses two fundamental areas in contemporary organic chemistry: synthesis of natural products and catalytic asymmetric synthesis. Firstly, a new methodology, developed by our research group, which allows the asymmetric synthesis of lactones, a structural unit ubiquitous in natural products, was utilised in the synthesis of a number of natural product analogues that showed signifi…
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- 978-3-319-20544-1
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Albumin in Medicine: Pathological and Clinical Applications
This book presents a comprehensive overview of medical and pharmaceutical applications of human serum albumin (HSA), with updates on structural aspects of albumin from the perspectives of X-ray crystallography and NMR, endogenous and exogenous ligand binding of albumin in various pathological conditions, and genetic variants and their phenotypes. Rapid progress and development of its applicatio…
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- Ed. 1
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- 978-981-10-2116-9
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- X, 277
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- 615 ALB a
Edible Medicinal and Non-Medicinal Plants
Volume 10 is part of a multi compendium Edible Medicinal and Non-Medicinal Plants. This work is of significant interest to medical practitioners, pharmacologists, ethnobotanists, horticulturists, food nutritionists, botanists, agriculturists, conservationists and general public. 59 plant species with edible modified stems, roots and bulbs in the families Amaranthaceae, Cannaceae, Cibotiaceae, C…
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- 1
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- 978-94-017-7275-4
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- X, 659
Edible Medicinal and Non-Medicinal Plants
This book covers such plants with edible modified storage subterranean stems (corms, rhizomes, stem tubers) and unmodified subterranean stem stolons, above ground swollen stems and hypocotyls, storage roots (tap root, lateral roots, root tubers), and bulbs, that are eaten as conventional or functional food as vegetables and spices, as herbal teas, and may provide a source of food additive o…
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- 978-3-319-26061-7
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- X, 392
Edible Medicinal and Non Medicinal Plants
Volume 9 is part of a multicompendium Edible Medicinal and Non-Medicinal Plants, on plants with edible modified stems, roots and bulbs from Acanthaceae to Zygophyllaceae (tabular) and 32 selected species in Alismataceae, Amaryllidaceae, Apiaceae, Araceae, Araliaceae, Asparagaceae, Asteraceae, Basellaceae, Brassicaceae and Campanulaceae in detail. This work is of significant interest to medical …
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- 978-94-017-9510-4
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- 73 b/w illustrations, 49 illustrations in colour
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- X, 1036
Multifaceted Roles of Crystallography in Modern Drug Discovery
The present work offers a snapshot of the state-of-the-art of crystallographic, analytical, and computational methods used in modern drug design and development. Topics discussed include: drug design against complex systems (membrane proteins, cell surface receptors, epigenetic targets, and ribosomes); modulation of protein-protein interactions; the impact of small molecule structures in drug d…
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- 1
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- 978-94-017-9718-4
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- XI, 240
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- NATO Science for Peace and Security Series A: Chemistry and Biology
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Synthesis and Vaccine Evaluation of the Tumor Associated Carbohydrate Antigen…
This thesis focuses on the synthesis and vaccine evaluation of the prostate tumor- associated carbohydrate antigen RM2. The author first presents the use of the [1+2+3] one-pot sequential strategy to successfully synthesise the RM2 antigen and its analogues as single stereoisomers in every glycosylation step, producing good yields and stereoselectivity. He then introduces the conjugation of the…
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- 978-3-662-46848-7
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- XIII, 108
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- Springer Theses
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