This volume details our current understanding of the architecture and signaling capabilities of known canonical and non-canonical inflammasome complexes and highlights their action, in particular in response to infection with important bacterial model organisms and the corresponding disease pathologies. The first chapters review new insights into the assembly and structures of inflammasome comp…
The present work focuses on the diagnosis of TB, covering all its possible ways. Content ranges from clinical diagnosis, which is the first instance in approaching tuberculosis, until the gold standard microbiological and molecular diagnostic tools, which are useful due to its speed and high sensitivity. Additionally, diagnosis of latent TB infection, which is key feature to controlling TB unde…
Bacterial diarrheal diseases remain an important leading cause of preventable death, especially among children under five in developing countries. In the American continent, diarrheal disease and other health complications caused by Escherichia coli constitute a major public health problem, and, therefore, several research groups have dedicated their effort to understand this pathogen and provi…
This Brief provides a comprehensive overview of Trypanosoma cruzi, a parasite that is traditionally considered as exclusively vectorborne, but can be foodborne, and may lead to outbreaks of Chagas disease in consumers. The characteristics of Trypanosoma cruzi and the clinical effects of the disease are covered, including documented outbreaks, regional patterns, and epidemiology. The various tra…
This volume focuses on those instances when benign and even beneficial relationships between microbes and their hosts opportunistically change and become detrimental toward the host. It examines the triggering events which can factor into these changes, such as reduction in the host’s capacity for mounting an effective defensive response due to nutritional deprivation, coinfections and seemi…
The book discusses new algorithms capable of searching for, tracking, mapping and providing a visualization of invisible substances. It reports on the realization of a bacterium-inspired robotic controller that can be used by an agent to search for any environmental spatial function such as temperature or pollution. Using the parameters of a mathematical model, the book shows that it is possibl…
The book is oriented towards undergraduates science and engineering students; postgraduates and researchers pursuing the field of microbiology, biotechnology, chemical - biochemical engineering and pharmacy. Various applications of microorganisms have been covered broadly and have been appropriately reflected in depth in 12 different chapters. The book begins with an insight to the diverse nich…
Foodborne illnesses caused by zoonotic pathogens associated with wildlife hosts are an emerging microbial food safety concern. Transmission of foodborne pathogens can occur through ingestion, or improper handling, of contaminated game meat. Wild and feral animals have also been investigated as potential sources of Campylobacter, Escherichia coli O157:H7 and other enteric pathogens following foo…
This volume summarizes recent advances in environmental microbiology by providing fascinating insights into the diversity of microbial life that exists on our planet. The first two chapters present theoretical perspectives that help to consolidate our understanding of evolution as an adaptive process by which the niche and habitat of each species develop in a manner that interconnects individua…
The type 2 immune response that develops during infectious disease has undergone major paradigm shifts in the last several years as new cell types and pathways have been identified. It is now clear that the type 2 immune response, characterized by elevations in specific cytokines, including IL-4, IL-5 and IL-13, is associated with helminth infections in both humans and mice. This response is co…