Kata pengantar; Pemilihan “Fungsi Seluler Protein Kinase CK2 dalam Keadaan Normal dan Penyakit” sebagai bagian dari seri Springer “Kemajuan Biokimia dalam Kesehatan dan Penyakit” (Volume 12) di bawah kepemimpinan Profesor Naranjan S. Dhalla menandai pengakuan akan pentingnya hal ini. Protein Kinase CK2 sebagai "pengatur utama" fungsi sel. Pentingnya Protein Kinase; Protein kinase adalah…
Kata pengantar; Buku pendek ini berasal dari makalah kami yang berjudul “MRFalign: Protein Homology Detection Through Alignment of Markov Random Fields,” yang memenangkan penghargaan makalah terbaik pada konferensi RECOMB 2014 dan juga diterbitkan di PLoS Computational Biology. Hal ini ditujukan bagi mahasiswa dan peneliti yang terlibat dalam pengembangan metode komputasi untuk analisis uru…
Selama beberapa dekade terakhir, para peneliti telah mencoba untuk memprediksi struktur protein tiga dimensi de novo dari rangkaian asam amino menggunakan parameter energetika lipat. Upaya juga difokuskan pada pemahaman interaksi protein-protein dan protein-ligan berdasarkan studi ini. Bab ini membahas faktor-faktor yang terlibat dalam pelipatan protein dan kontribusinya terhadap energi pelipat…
This book addresses the differentiation control of skeletal muscle in different locations of the vertebrate body Particular attention is paid to novel regulatory molecules and signals as well as the heterogeneity of origin that have revealed a developmental overlap between skeletal and cardiac muscle. Different functional muscle groups are the product of the evolution of the vertebrate classes,…
Ion channels are the major class of membrane proteins responsible for rapid and regulated transport of ions across biological membranes and for the generation and propagation of electrical signals in the brain, heart, and skeletal and vascular tissues. Ion channels are also known to play critical roles in regulation of cell proliferation, insulin secretion and intracellular signaling in a varie…
The Nordic countries have collaborated in setting guidelines for dietary composition and recommended intakes of nutrients for several decades through the joint publication of the Nordic Nutrition Recommendations (NNR). This 5th edition, the NNR 2012, gives Dietary Reference Values (DRVs) for nutrients, and compared with earlier editions more emphasis has been put on evaluating the scientific ev…
Na+-K+ ATPase or Na-pump ATPase, a member of “P”-type ATPase superfamily, is characterized by association of multiple isoforms mainly of it’s α- and β- subunits. At present four different α- (α-1,α-2,α-3 and α-4) and three β- (β-1, β-2, and β-3) isoforms have been identified in mammalian cells and their differential expressions are tissue specific. Regulation of Na+-K+ ATPase a…