Antimicrobial peptides are key defense molecules adopted by all life forms to prevent infection. They also have other beneficial effects such as boosting immune response, anticancer, and wound healing. The antiviral effects of antimicrobial peptides have laid the foundations for developing new agents to combat seasonal Flu, HIV-1, RSV, Zika, and Ebola. This eBook is constructed to systematicall…
Stroke, a progressively non-communicable disease, is the second leading cause of death after coronary heart disease in developed countries. The present treatment options for stroke are adapting lifestyle practices, diabetes treatment, drugs, and the management of other factors, but no cure is yet available, despite new insights into molecular and therapeutic targets. Discoveries related to expl…
The year 2017 marks the 20th anniversary of the molecular cloning of the long sought-after capsaicin receptor, now known as TRPV1 (Transient Receptor Potential Vanilloid 1). This seminal discovery has opened up a “hot” new field of basic research and launched drug discovery efforts into the large family (by the latest count, 28 mammalian members and 27 in humans) of TRP ion channels. Indeed…
The present book discusses in detail the nature and bioactive properties of lichen secondary metabolites. Their therapeutic potential ranges from antibiotic to antioxidant and from anticarcinogenic to antiviral activity. It further discusses their use in traditional medicine and highlights possible future directions in the study of their pharmaceutical potential.
Until recently, it was thought that the adult brain is modifiable only during early stages of ontogenesis. However, neurophysiological and neuroimaging studies now indicate that the mature human brain is, under certain conditions, capable of substantial neuroplastic changes. Neuroplasticity reflects the ability of the human brain to alter the pattern of neural activation in response to previous…
This cutting-edge book will cover various aspects of headache management, with a focus on difficult patients. Practical, step-by-step advice for treating challenging headaches, including migraine, refractory and cluster headaches, will be provided in detail along with how to approach patients of different ages and those with psychological disorders. Unique and complex case studies and complet…
This book examines the words and discourse as well as their meaning and impact on the everyday culture of a multidisciplinary team at a school for students with mental disabilities. The book examines the organizational, social, professional, and emotional experiences of team members from such disciplines as child and school psychology, special education, therapy (e.g., occupational, speech), so…
Provides up-to-date descriptions of treatments and treatment outcomes Focuses especially on integrated treatments Will aid surgeons, oncologists, gynecologists, pathologists, and residents in daily clinical practice and research Includes numerous high quality illustrations and tables
This comprehensive volume provides current state of the art of the use of corticosteroids in the pediatric patient. It consists of 14 chapters written by leading authors from different countries. The first chapters cover historical notes, general concepts on treatment with corticosteroids with regard to indications and side effects, and basic pharmacologic properties of these compounds. The res…
The renin angiotensin system is implicated in the progression of atherosclerotic disease as well as of left ventricular dysfunction. Angiotensin converting enzyme inhibitors and AT1 receptor antagonists have been proven to reduce morbidity and mortality in patients with left ventricular dysfunction or in those at high cardiovascular risk with preserved ventricular function. This book is intende…