This open access book focuses on the molecular mechanism of congenital heart disease and pulmonary hypertension, offering new insights into the development of pulmonary circulation and the ductus arteriosus. It describes in detail the molecular mechanisms involved in the development and morphogenesis of the heart, lungs and ductus arteriosus, covering a range of topics such as gene functions, g…
This is an open access book. This book presents new theory and methods on compiling lithofacies paleogeographic maps as a key tool for guiding geological survey on shale gas. The fundamental goal of the shale gas geological survey is to find the ‘dessert’ area. It is therefore suggested that the lithofacies paleogeographic study and the technique of mapping should be a solid scientific basi…
One of the grand challenges the logistics industry is facing today is the question of how to limit the negative impact of freight transport. Freight transport demand is continuously rising and must be satisfied by logistics. The ever-increasing share of trucks is problematic due to the high external costs of road transport. European politics has dedicated itself to these problems and shows …
This open access book is based on "Spationomy – Spatial Exploration of Economic Data", an interdisciplinary and international project in the frame of ERASMUS+ funded by the European Union. The project aims to exchange interdisciplinary knowledge in the fields of economics and geomatics. For the newly introduced courses, interdisciplinary learning materials have been developed by a team of…
This open access publication presents a global panorama of institutional strategies, academic programs, scholarly insights as well as teaching and learning practices taking stock of the Future Skills Turn taking place in higher education. Future Skills have evolved to be one of the most important priorities for the development of higher education institutions globally. Students and graduates le…
Chimeric antigen receptor T cell therapy (CAR-T) is a new class of medicinal products that are genetically engineered from T cells. It is expected that other forms of Immune Effector Cells-based therapies will soon reach the market, manufactured from other subsets of immune cells, and engineered through other technologies than currently used defective retroviral or lentiviral vectors. Ce…
How to deal with carbon emissions—a rare externality that spans a large time frame and geographical scope—is a difficult task for the world. This task is particularly challenging for China, mainly in that the country must coordinate dual objectives, including existing economic growth targets and the newly added carbon neutrality goal. Over the past 40 years of reform and opening up, Chi…
Noncommunicable diseases (NCDs) are responsible for 71% of deaths globally and, among them, cardiovascular diseases (CVDs) are the leading cause of death, accounting for almost 44%, followed by cancer with 22%, respiratory diseases with 9%, and diabetes with 4% (World Health Organization n.d.-a). According to the World Health Organization (WHO) 15 million people, aged between 30 and 69Â…
This Open access book offers updated and revised information on vessel health and preservation (VHP), a model concept first published in poster form in 2008 and in JVA in 2012, which has received a great deal of attention, especially in the US, UK and Australia. The book presents a model and a new way of thinking applied to vascular access and administration of intravenous treatment, and …
This open access book is the first comprehensive overview of maritime or marine spatial planning. Countries across the globe are beginning to implement maritime spatial plans; however the authors of this collection have identified several key questions that are emerging from this growing body of MSP experience. How can maritime spatial planning deal with a complex and dynamic environment such a…