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Biobetters : Protein Engineering to Approach the Curative
“Biobetters: Protein Engineering to Approach the Curative” discusses the optimization of protein therapeutic products for treatment of human diseases. It is based on the fact that though numerous important therapeutic protein products have been developed for life threatening and chronic diseases that possess acceptable safety and efficacy profiles, these products have generally not been ree…
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- 610.28
The Floating Strip Micromegas Detector
This book discusses a novel and high-rate-capable micro pattern gaseous detector of the Micromegas (MICRO-MEsh GAS detector) type. It provides a detailed characterization of the performance of Micromegas detectors on the basis of measurements and simulations, along with an in-depth examination of analysis and reconstruction methods. The accurate and efficient detection of minimum ionizing parti…
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- 978-3-319-18893-5
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- XV, 256
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- Springer Theses
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Understanding Phase Contrast MR Angiography A Practical Approach with MATLAB…
Providing many unique MATLAB codes and functions throughout, this book covers the basics of Magnetic Resonance Imaging (MRI), leading to an in-depth understanding of the concepts and tools required for analysis and interpretation of Phase Contrast MR Angiography (PC-MRA). The concept of PC-MRA is often difficult, but essential for practicing engineers and scientists working in MR related areas.…
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- 978-3-319-25483-8
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- 13 b/w illustrations, 39 illustrations in colour
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Uncertainty in Biology A Computational Modeling Approach
Computational modeling allows to reduce, refine and replace animal experimentation as well as to translate findings obtained in these experiments to the human background. However these biomedical problems are inherently complex with a myriad of influencing factors, which strongly complicates the model building and validation process. This book wants to address four main issues related to the bu…
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- 978-3-319-21296-8
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- IX, 478
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How to Write a Competitive R01 Grant
This book describes the process of completing an NIH R01 grant application. It begins with the formation of an idea and proceeds through the subsequent stages: verifying the idea’s strength and potential, collecting high-quality preliminary data, networking for feedback, writing the first and subsequent drafts of the application (including details on what to include and tips on content and t…
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- 978-3-319-41359-4
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- X, 64
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- 610 DEY h
Tumor Microenvironment Study Protocols
This volume covers the topics presented at the 3rd International Conference on Tumor Microenvironment and Cellular Stress by an international community of researchers. The conference brings together scientists to discuss different cellular and animal models of tumor microenvironment study and identify common pathways that are candidates for therapeutic intervention; stimulate collaboration betw…
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- 978-3-319-26666-4
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- 21 b/w illustrations, 64 illustrations in colour
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Tumor Cell Metabolism Pathways, Regulation and Biology
The four sections of this book cover cell and molecular biology of tumor metabolism, metabolites, tumor microenvironment, diagnostics and epigenetics. Written by international experts, it provides a thorough insight into and understanding of tumor cell metabolism and its role in tumor biology. The book is intended for scientists in cancer cell and molecular biology, scientists in drug and diagn…
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- 978-3-7091-1824-5
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- 17 b/w illustrations, 35 illustrations in colour
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Tryptophan Metabolism: Implications for Biological Processes, Health and Disease
This book discusses the relationship between cellular immunity and tryptophan metabolism, as well as its products, serotonin and melatonin, in the development of several diseases and reappraises the common signal transduction pathways of the neurodegenerative diseases, carcinogenesis, immune tolerance, inflammation, hypersensitivity reactions, neuropsychiatric disorders, in addition to bacteria…
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- 978-3-319-15630-9
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- 4 b/w illustrations, 17 illustrations in colour
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FXTAS, FXPOI, and Other Premutation Disorders
This book should serve as a resource for professionals in all fields regarding diagnosis, management, and counseling of patients with FXTAS, FXPOI and their families, as well as presenting the molecular basis for disease that may lead to the identification of new markers to predict disease risk and eventually lead to target treatments. The book will present information on all aspects of FXTA…
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- 978-3-319-33898-9
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- 10 b/w illustrations, 12 illustrations in colour
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Extremophiles and Their Applications in Medical Processes
Extremophiles are known to thrive under harsh environmental conditions. Many extremophilic bio-products are already used as life-saving drugs. Recent technological advancements of systems biology have opened the door to explore these organisms anew as sources of products that might prove useful in clinical, environmental and drug development.
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- 978-3-319-12808-5
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- 8 illustrations in colour
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