This volume presents a selection of case studies that address a substantial range of optimized object packings (OOP) and their applications. The contributing authors are well-recognized researchers and practitioners. The mathematical modelling and numerical solution aspects of each application case study are presented in sufficient detail. A broad range of OOP problems are discussed: these incl…
Recent developments in theory, algorithms, and applications in optimization and control are discussed in this proceedings, based on selected talks from the ‘Optimization Control and Applications in the Information Age’ conference, organized in honor of Panos Pardalos’s 60th birthday. This volume contains numerous applications to optimal decision making in energy production and fuel manage…
This book presents the latest findings on stochastic dynamic programming models and on solving optimal control problems in networks. It includes the authors’ new findings on determining the optimal solution of discrete optimal control problems in networks and on solving game variants of Markov decision problems in the context of computational networks. First, the book studies the finite state…
This book presents recent results on positivity and optimization of polynomials in non-commuting variables. Researchers in non-commutative algebraic geometry, control theory, system engineering, optimization, quantum physics and information science will find the unified notation and mixture of algebraic geometry and mathematical programming useful. Theoretical results are matched with algorithm…
Very little has been published on optimization of pharmaceutical portfolios. Moreover, most of published literature is coming from the commercial side, where probability of technical success (PoS) is treated as fixed, and not as a consequence of development strategy or design. In this book there is a strong focus on impact of study design on PoS and ultimately on the value of portfolio. Design …
The subject of this book is supply chain logistics planning optimization under multiple uncertainties, the key issue in supply chain management. Focusing on the strategic-alliance three-level supply chain, the model of supply chain logistics planning was established in terms of the market prices and the market requirements as random variables of manufactured goods with random expected value…
This book constitutes the proceedings of the 12th International Conference on the Integration of Artificial Intelligence (AI) and Operations Research (OR) Techniques in Constraint Programming, CPAIOR 2015, held in Barcelona, Spain, in May 2015. The 29 papers presented together with 8 short papers in this volume were carefully reviewed and selected from 90 submissions. The purpose of the confere…
This is a thorough revision of the 2007 publication, and includes five new chapters and brings all existing chapters completely up to date. There have been many advances in hydropower and renewable technologies since the original publication, and Europe, and particularly Scandinavia, plan many more in the coming years. From a review of the original edition: “… it is important to …
This monograph, written by well renowned breast cancer expect, Dr. Jose Russo, provides new insight on the pathobiology of breast cancer from the most current advances in the field, translational research, initiation and progression of the disease, the mechanism of invasion and metastasis and the concept of stem cells in treatment and drug resistance. The role of personalized medicine and genom…
As the first primer on the effects of exercise on human hypertension, Effects of Exercise on Hypertension: From Cells to Physiological Systems provides the state-of-the-art effects of exercise on the many possible mechanisms underlying essential hypertension in humans. The book contains chapters by distinguished experts on the effects of exercise on physiological systems known to be involved in…