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Translational Research in Audiology, Neurotology, and the Hearing Sciences
Translational Research is the interface between basic science and human clinical application, including the entire process from animal studies to human clinical trials (phases I, II, and III). Translational Research moves promising basic science results from the laboratory to bedside application. Yet, this transition is often the least-defined, least-understood part of the research process. Mos…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-40846-0
- Collation
- XVIII, 265
- Series Title
- Springer Handbook of Auditory Research
- Call Number
- -
Evaluating e-Participation Frameworks, Practice, Evidence
There is a widely acknowledged evaluation gap in the field of e-participation practice and research, a lack of systematic evaluation with regard to process organization, outcome and impacts. This book addresses the state of the art of e-participation research and the existing evaluation gap by reviewing various evaluation approaches and providing a multidisciplinary concept for evaluating the o…
- Edition
- -
- ISBN/ISSN
- 978-3-319-25403-6
- Collation
- 13 b/w illustrations, 26 illustrations in colour
- Series Title
- -
- Call Number
- -
Translational Research Methods for Diabetes, Obesity and Cardiometabolic Drug…
The world is beset by a pandemic of obesity and type 2 diabetes and the need for new drugs is startlingly clear; recent years have seen a huge increase in research activity to fill this gap. The development of new drugs for diabetes and obesity must be founded upon a sound appreciation of the pathophysiology of these common disorders. The dual defects of insulin resistance and impaired insulin …
- Edition
- 1
- ISBN/ISSN
- 978-1-4471-7032-7
- Collation
- XII, 312
- Series Title
- -
- Call Number
- -
Membrane Protein – Lipid Interactions: Physics and Chemistry in the Bilayer
This book has been conceives as a brief introduction to biomembranes physical chemistry for undergraduate students of sciences, and it is particularly dedicated to the lipid-protein membrane interactions. A general introduction is presented in Chapters 1 and 2. The following Chapters, 3 and 4, describe the most accepted theories on lipid-membrane protein interactions as well as the new experime…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-30275-1
- Collation
- XIV, 116
- Series Title
- Membrane Protein – Lipid Interactions: Physics and Chemistry in the Bilayer
- Call Number
- -
Translational Neuroscience
Translational Neuroscience offers a far-reaching and insightful series of perspectives on the effort to bring potentially revolutionary new classes of therapies to the clinic, thereby transforming the treatment of human nervous system disorders. Great advances in the fields of basic neuroscience, molecular biology, genomics, gene therapy, cell therapy, stem cell biology, information technology,…
- Edition
- 1
- ISBN/ISSN
- 978-1-4899-7652-9
- Collation
- XV, 584
- Series Title
- -
- Call Number
- -
Translational Neuropsychopharmacology
This book covers wide areas of animal and human psychopharmacology with clinical utility in the treatment of psychiatric and neurological (e.g Alzheimer's disease) disorders. The main theme is to develop a new paradigm for drug discovery that questions the claim that animal models or assays fail adequately to predict Phase 3 clinical trials. A new paradigm is advocated that stresses the importa…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-33911-5
- Collation
- XII, 498
- Series Title
- Current Topics in Behavioral Neurosciences
- Call Number
- -
Translational Informatics
Integrative and translational methodologies and frameworks have transformed modern biomedical research and the delivery of clinical care. This shift has been manifested in a number of ways, including the rapid growth and increasing availability of high-throughput bio-molecular instrumentation and analysis platforms, innovative clinical research programs intended to accelerate knowledge translat…
- Edition
- 1
- ISBN/ISSN
- 978-1-4471-4646-9
- Collation
- IX, 185
- Series Title
- Health Informatics
- Call Number
- -
Translational Biomedical Informatics
This book introduces readers to essential methods and applications in translational biomedical informatics, which include biomedical big data, cloud computing and algorithms for understanding omics data, imaging data, electronic health records and public health data. The storage, retrieval, mining and knowledge discovery of biomedical big data will be among the key challenges for future transla…
- Edition
- 1
- ISBN/ISSN
- 978-981-10-1503-8
- Collation
- VI, 332
- Series Title
- Advances in Experimental Medicine and Biology
- Call Number
- -
Translational Approaches to Autism Spectrum Disorder
This book addresses and synthesizes recent basic, translational, and clinical research with the goal of understanding the mechanisms behind autism spectrum disorder (ASD) and how they lead to altered brain function and behavior. Bringing clarity to these mechanisms will lead to more effective therapies for the various heterogeneous pathologies that comprise ASD. Currently there are few, if any,…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-38657-7
- Collation
- XIV, 218
- Series Title
- -
- Call Number
- -
Evacuation Modeling Trends
This book presents an overview of modeling definitions and concepts, theory on human behavior and human performance data, available tools and simulation approaches, model development, and application and validation methods. It considers the data and research efforts needed to develop and incorporate functions for the different parameters into comprehensive escape and evacuation simulations, wit…
- Edition
- -
- ISBN/ISSN
- 978-3-319-20708-7
- Collation
- VII, 133
- Series Title
- -
- Call Number
- -
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