Written and edited by some of the world’s leading experts on N-of-1 trials, the book presents state of the art knowledge about N-of-1 trials, with chapters on ethics, statistics, health economics, design, analysis and reporting, and more. Full of examples and well illustrated, it is a comprehensive compendium of issues surrounding the design, conduct, interpretation and implementation of N-o…
This book examines the nature and consequences of strategic competition between the US and China, which affects the global security landscape and the emerging security architecture across the broader Asia-Pacific region. The author illustrates the evolution of Sino-US security interactions from the anti-Soviet alliance, to temporary marginalization, to eventual strategic competition and examine…
This book covers the major problems of turbulence and turbulent processes, including physical phenomena, their modeling and their simulation. After a general introduction in Chapter 1 illustrating many aspects dealing with turbulent flows, averaged equations and kinetic energy budgets are provided in Chapter 2. The concept of turbulent viscosity as a closure of the Reynolds stress is also i…
This thesis addresses the intriguing topic of the quantum tunnelling of many-body systems such as Bose-Einstein condensates. Despite the enormous amount of work on the tunneling of a single particle through a barrier, we know very little about how a system made of several or of many particles tunnels through a barrier to open space. The present work uses numerically exact solutions of the time-…
This book discusses the relationship between cellular immunity and tryptophan metabolism, as well as its products, serotonin and melatonin, in the development of several diseases and reappraises the common signal transduction pathways of the neurodegenerative diseases, carcinogenesis, immune tolerance, inflammation, hypersensitivity reactions, neuropsychiatric disorders, in addition to bacteria…
Taking an interdisciplinary approach to conceptualise interpersonal trust between patients and medical practitioners, Katja Beitat introduces a unique model to describe the dynamics of trust building and deterioration with particular relevance to incidents in health care. Empirical findings from studies in Australia and Germany, the two systems focused on in this book, broadly support and expan…
This monograph presents the latest findings from a long-term research project intended to identify the physics behind Quantum Mechanics. A fundamental theory for quantum mechanics is constructed from first physical principles, revealing quantization as an emergent phenomenon arising from a deeper stochastic process. As such, it offers the vibrant community working on the foundations of quantum …
This book focuses on the taxonomic diversity of the genus Tuber as economically important truffles. In contributions by internationally respected scientists, it examines truffle systematics, interactions with abiotic and biotic environments, strategies for spore dispersal, and molecular processes in truffles. Topics discussed include: evolutionary theories and phylogeny of Tuber species from As…
Furthermore, Duhem felt, in criticizing such a theory one must guard against narrowness of mind and petty corrections which would make one forget the merit of the inventor; and, more importantly, one must guard against the blind superstition which, for admiration of the author, would hide the serious defects of the work. He is not so great a genius that he surpasses the laws of reason. Pierr…
This book presents the latest information on tropical tree physiology, making it a valuable research tool for a wide variety of researchers. It is also of general interest to ecologists (e.g. Ecological Society of America; > 3000 or 4000 members at annual meeting), physiologists (e.g. American Society of Plant Biologists; > 2,000 members at annual meeting), and tropical biologists (e.g. Associa…