The topic of this book is one of the most contentious, complex and at the same time very important in many respects. Latest achievements in the biotechnology industry related to the stem cell technology are quite important. On the one hand, human embryonic stem cells are viewed as strong tools to be applied for curing or at least alleviating of until now not curable illnesses, such as Alzheimer…
The Cold War produced in many countries a form of political repression and societal paranoia which often infected governmental and civic institutions. In the West, the driving catalyst for the phenomenon was anti-communism. While much has been written on the post-war American red scare commonly known as McCarthyism, the domestic British response to the ‘red menace’ during the early Cold War…
This open access book offers a framework for understanding how the Holocaust has shaped and continues to shape medical ethics, health policy, and questions related to human rights around the world. The field of bioethics continues to face questions of social and medical controversy that have their roots in the lessons of the Holocaust, such as debates over beginning-of-life and medical genetics…
The available parenteral and oral anticoagulants have a large clinical use. Understanding biochemistry of anticoagulants may help to improve therapeutic strategies. Resistance to vitamin K antagonist drugs might be a problem for rodent populations. Patients who have thrombogenic risk factors should be anticoagulated. The need for cardiac implantable electronic devices is increasing, and there i…
In this book, you'll find the latest updates about the current use of anticoagulants in medical practice. This includes clinical pharmacotherapy, laboratory monitoring, and antidotes. You'll also find a special focus on heparin-induced thrombocytopenia, including various mechanisms and presentations. Finally, you'll find important details that will help you to understand what patients receiving…
Thrombotic diseases are some of the leading causes of death in the world. Anticoagulation is a mainstay approach for the prophylaxis and treatment of thrombotic diseases. This book includes six chapters regarding the mechanisms of anticoagulation and its clinical value in different disease conditions. The first two chapters summarize the general information regarding anticoagulation and hyperco…
This open access book analyzes the main drivers that are influencing the dramatic evolution of work in Asia and the Pacific and identifies the implications for education and training in the region. It also assesses how education and training philosophies, curricula, and pedagogy can be reshaped to produce workers with the skills required to meet the emerging demands of the Fourth Industrial Rev…
The Special Issue "Anticancer Drugs 2021" of Pharmaceuticals is focused on recent significant advances in the design, synthesis, molecular mechanism of action and therapeutic applications of anticancer drugs. This collection of preclinical research papers and reviews includes designed chemotherapeutic agents, targeted therapies and biological agents. The rationalization for the biological activ…
This open access book addresses a variety of issues relating to bioethics, in order to initiate cross-cultural dialogue. Beginning with the history, it introduces various views on bioethics, based on specific experiences from Japan. It describes how Japan has been confronted with Western bioethics and the ethical issues new to this modern age, and how it has found its foothold as it decides whe…
The past decades have seen major developments in the understanding of the cellular and molecular biology of cancer. Significant progress has been achieved regarding long-term survival for the patients of many cancers with the use of tamoxifen for treatment of breast cancer, treatment of chronic myeloid leukaemia with imatinib, and the success of biological drugs. The transition from cytotoxic c…