N-of-1 trials, a type of individualized randomized controlled trial, are relevant to almost every discipline in medicine and psychology. They can tell the clinician with precision whether a treatment works in that individual, which distinguishes from the information available from most other trial designs. They have the potential to revolutionize the way clinical medicine is practiced. Whet…
Since its third edition in 1980, the Diagnostic and Statistical Manual of Mental Disorders (DSM) of the American Psychiatric Association has acquired a hegemonic role in the health care professions and has had a broad impact on the lay public. The publication in May 2013 of its fifth edition, the DSM-5, marked the latest milestone in the history of the DSM and of American psychiatry. In The DSM…
Based on 30 years of clinical and research experience, backed by a careful assessment of four decades of published data, Dr. Faguet documented in The War on Cancer (Springer 2005), early advances in cancer treatment and patient survival that soon stalled. Ten years later and after an exhaustive analysis of evidence-based data available through 2013 that incorporates 755 references, he reveals t…
Drawing on interdisciplinary, cross-national perspectives, this open access book contributes to the development of a coherent scientific discourse on social exclusion of older people. The book considers five domains of exclusion (services; economic; social relations; civic and socio-cultural; and community and spatial domains), with three chapters dedicated to analysing different dimensions of …
Life is short, art long: The art of healing in Byzantium. New perspectives. Providing new approaches to Byzantine views on health and medicine, this 13-chapter volume builds interdisciplinary bridges between a variety of subjects, ranging from religious beliefs and supernatural forces to oral health and dietary habits. Other topics include perceptions of the eternal afterlife, health centers in…
Winner of BMA Medical Book Award, Highly Commended in Public Health Written for medical professionals, this book provides a concise reference with clear guidelines on how to manage both the victims of chemical agent exposure and the site of the incident. David Baker considers the nature and basic science of the hazards faced as well as the practical management of persons exposed to chemicals…
In 2009 the University Medicine Greifswald launched the “Greifswald Approach to Individualized Medicine” (GANI_MED) to implement biomarker-based individualized diagnostic and therapeutic strategies in clinical settings. Individualized Medicine (IM) has led not only to controversies about its potentials, but also about its societal, ethical and health economic implications. This anthology fo…
This chapter seeks to situate James Butler, duke of Ormond, at the centre of an important patronage network for medicine in Restoration Britain and Ireland. It explores the Irish dimension of the emergence of the Society of Chemical Physicians and situates it against the background provided by the momentous Cromwellian period in Ireland. Particular attention is paid to Pierre Belon, a Huguenot …
This book covers the mechanisms of renal cyst development as well as the aberrant signaling pathways which are involved in Autosomal Dominant Polycystic Kidney Disease (ADPKD). ADPKD is a genetic disease in which cysts appear in the epithelial lining of both kidneys. End stage ADPKD patients experience renal failure and require dialysis or a renal transplantation. There are no specific targeted…
In medical terms, 'mineral water' was, in the early nineteenth century, any water that appeared to have an effect on human health. British physicians often prescribed mineral waters from particular locations - most commonly those at Bath - for a variety of illnesses. However, there was little available information on the chemical composition of these waters, and extant manuals were often inaccu…