In Western countries, cancer is among the most frequent causes of death. Despite striking advances in cancer therapy, especially by the so called “targeted agents”, there is still an urgent need for new drugs in oncology. Hope comes from the marine environment, which is a rich source of natural compounds showing anti-cancer activity. To date, four marine cytotoxic substances, namely cytarab…
Dietary intake in children is not only associated with current and future health, but also with behavior and learning. Especially during early childhood and throughout the school-age years, adequate food and nutrient intake to support brain development and function are critical. Data on the effect of sugar intake on children’s activity levels, or their ability to focus on cognitive tasks, are…
Buku Metode Kimia dalam Penetration Enhancement: Modifikasi Stratum Korneum menjelaskan metode kimia yang digunakan dalam penetration enhancement obat-obatan dengan penekanan pada metode peningkat yang digunakan untuk memodifikasi stratum korneum. Ini dimulai dengan klasifikasi peningkat penetrasi, cara kerjanya, dan memberikan wawasan tentang hubungan struktur-aktivitas peningkat penetrasi ki…
Tujuan dari seri buku ini adalah untuk memberikan kepada pembaca yang bekerja di dunia akademis dan industri, termasuk peneliti muda, sebuah karya komprehensif terkini yang menjelaskan semua topik penting yang diperlukan untuk memahami prinsip-prinsip peningkatan pemberian obat transdermal dan dermal. Seri buku tersebut berisi lima buku. Buku Metode Kimia dalam Penetration Enhancement: Strategi…
Your alarm goes off and, after hitting “snooze” once or twice, you pry yourself out of bed. You make a cup of coffee to help you get going, and then you shower, get dressed, eat breakfast, and check your phone for messages. On your way to school, you stop to fill your car’s gas tank, almost making you late for the first day of chemistry class. As you find a seat in the classroom, you r…
This thesis lays the groundwork for the automatic supervision of the laser incision process, which aims to complement surgeons’ perception of the state of tissues and enhance their control over laser incisions. The research problem is formulated as the estimation of variables that are representative of the state of tissues during laser cutting. Prior research in this area leveraged numerical …
This book provides an overview of the role and function of regulatory RNAs that lack protein-coding potential in key reproductive tissues. This includes the role of small interfering RNAs (siRNAs), microRNAs (miRNAs), PIWI-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs) and long non-coding RNAs (lncRNAs). Through clear, detailed and comprehensive debate, international leading experts …
Bridging the gap between the medical literature and the practice of lumbar spine medicine, this user-friendly, accessible text describes the causes of lower back pain and associated “sciatic” pathologies and how these problems can be successfully treated without surgery. Beginning with a review of the anatomy of the lumbar spine and the most common causes of lower back pain, diagnostic and …
Non-Invasive Sperm Selection for In Vitro Fertilization summarizes and discusses the relevant literature on the various advanced sperm selection methods used in modern Assisted Reproductive Technologies (ART). Chapters review some of the major unresolved issues in the field, the feasibility and success of the various sperm selection methods, their safety and the effects they have on sperm quali…
This comprehensive resource brings together the most current theories, evidence and best practice parameters for the use of nocturnal non-invasive ventilation (nNIV). Chapters focus on the application of acute and chronic nNIV in patients with cardio-respiratory disorders over a range of major medical settings. Updates on past and recent research in this field are highlighted. Authored by leadi…