This book investigates several duality approaches for vector optimization problems, while also comparing them. Special attention is paid to duality for linear vector optimization problems, for which a vector dual that avoids the shortcomings of the classical ones is proposed. Moreover, the book addresses different efficiency concepts for vector optimization problems. Among the problems that app…
This book provides information on best practices and new thinking regarding the validation of alternative methods for toxicity testing. It covers the validation of experimental and computational methods and integrated approaches to testing and assessment. Validation strategies are discussed for methods employing the latest technologies such as tissue-on-a-chip systems, stem cells and transcript…
In his study, Jan Posthumus uses the grounded theory method to explore the implementation of marketing instruments such as segmentation and targeting in the recruitment of high potentials in the pharmaceutical industry. The implementation of these instruments can best be understood as the result of an interaction between four categories: the identified internal need for certain groups of high p…
This book reviews classical epidemiological and clinical research studies, with a focus on aging. Chapters cover methodological topics like the scientific method, ethics, and the consequences of certain exclusion criteria and the work includes a look at clinical concepts like multi morbidity, frailty and functionality. The authors reveal the issues and challenges for researchers of age and agin…
This book systematically summarizes the ideas and technologies used in urine proteome analysis. It argues that change is the core of biomarker definition since the body uses its homeostatic mechanisms to correct changes in the blood. This means that urine is probably a better source of biomarkers than blood. A roadmap to the urinary biomarker era is proposed, and researchers are reminded of the…
This Brief integrates the literature and research on other-oriented hope. It discusses the position of other-oriented hope as one manifestation of the broader attribute of other-interest and argues the importance of other-interest in well-being. The Brief examines definitions and attributes of other-oriented hope, based upon theoretical and empirical understandings of hope more generally. There…
When no samples are available to estimate a probability distribution, we have to invite some domain experts to evaluate the belief degree that each event will happen. Perhaps some people think that the belief degree should be modeled by subjective probability or fuzzy set theory. However, it is usually inappropriate because both of them may lead to counterintuitive results in this case. In o…
This book aims at illustrating strategies to account for uncertainty in complex systems described by computer simulations. When optimizing the performances of these systems, accounting or neglecting uncertainty may lead to completely different results; therefore, uncertainty management is a major issues in simulation-optimization. Because of its wide field of applications, simulation-optimiz…
This book introduces methods for uncertain multi-attribute decision making including uncertain multi-attribute group decision making and their applications to supply chain management, investment decision making, personnel assessment, redesigning products, maintenance services, military system efficiency evaluation. Multi-attribute decision making, also known as multi-objective decision making w…
This book is intended to present the milestones in the progression of uncertain Data envelopment analysis (DEA). Chapter 1 gives some basic introduction to uncertain theories, including probability theory, credibility theory, uncertainty theory and chance theory. Chapter 2 presents a comprehensive review and discussion of basic DEA models. The stochastic DEA is introduced in Chapter 3, in which…