Blindness and visual impairment impact significantly on an individual’s physical and mental well-being. Loss of vision is a global health problem, with approximately 250 million of the world’s population currently living with vision loss, of which 36 million are classified as blind. Visual impairment is more frequent in the elderly, with cataract and age-related macular degeneration (AMD) a…
This book has been created to provide a framework for building your skills in writing and critical thinking. It provides access to published samples from professional authors along with essay drafts from ESL students who have polished their skills in their respective writing courses. The themes in the readings will give you a variety of topics to discuss with your classmates, which may inspi…
Nuclear Magnetic Resonance (NMR) spectroscopy is a nondestructive technique that can be used to characterize a wide variety of systems. Sustained development of both methodology and instrumentation have allowed NMR to evolve as a powerful technology, with applications in pure sciences, medicine, drug development, and important branches of industry. NMR provides precise structural information do…
This is the first book to provide a broad framework for obtaining an in depth understanding of the state-of-the-art knowledge on abnormalities of non-coding RNAs found to be associated with colorectal cancer pathogenesis. Readers will discover possible mechanisms underlying the substantial roles played by non-coding RNAs in molecular hallmarks of colorectal cancer.This work further provides the…
This book presents a state-of-the-art compilation of articles on the role of non-coding RNAs as pivotal molecules for establishing functional relationships between different organisms. It also describes how non-coding RNA molecules can act as dynamic communication devices and how they modulate the interaction between different kingdoms. It describes examples including viruses, bacteria, fungi, …
This book provides an overview of the role and function of regulatory RNAs that lack protein-coding potential in key reproductive tissues. This includes the role of small interfering RNAs (siRNAs), microRNAs (miRNAs), PIWI-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs) and long non-coding RNAs (lncRNAs). Through clear, detailed and comprehensive debate, international leading experts …
Bridging the gap between the medical literature and the practice of lumbar spine medicine, this user-friendly, accessible text describes the causes of lower back pain and associated “sciatic” pathologies and how these problems can be successfully treated without surgery. Beginning with a review of the anatomy of the lumbar spine and the most common causes of lower back pain, diagnostic and …
The book focuses on the part of the audio conversation not related to language such as speaking rate (in terms of number of syllables per unit time) and emotion centric features. This text examines using non-linguistics features to infer information from phone calls to call centers. The author analyzes "how" the conversation happens and not "what" the conversation is about by audio signal proce…
This monograph describes the numerical analysis of non-linearities in structural mechanics, i.e. large rotations, large strain (geometric non-linearities), non-linear material behaviour, in particular elasto-plasticity as well as time-dependent behaviour, and contact. Based on that, the book treats stability problems and limit-load analyses, as well as non-linear equations of a large number of …
In the current economic scenario, the intangible assets contribute significantly to the construction of the competitive positioning of a company. It follows that this intangible information must be appropriately considered in the internal rating system (IRSs). Currently key aspects of business risk and operational risk such as potential for growth, competitive capabilities, core competencies, r…