This book systematically summarizes the ideas and technologies used in urine proteome analysis. It argues that change is the core of biomarker definition since the body uses its homeostatic mechanisms to correct changes in the blood. This means that urine is probably a better source of biomarkers than blood. A roadmap to the urinary biomarker era is proposed, and researchers are reminded of the…
This Brief integrates the literature and research on other-oriented hope. It discusses the position of other-oriented hope as one manifestation of the broader attribute of other-interest and argues the importance of other-interest in well-being. The Brief examines definitions and attributes of other-oriented hope, based upon theoretical and empirical understandings of hope more generally. There…
When no samples are available to estimate a probability distribution, we have to invite some domain experts to evaluate the belief degree that each event will happen. Perhaps some people think that the belief degree should be modeled by subjective probability or fuzzy set theory. However, it is usually inappropriate because both of them may lead to counterintuitive results in this case. In o…
This book aims at illustrating strategies to account for uncertainty in complex systems described by computer simulations. When optimizing the performances of these systems, accounting or neglecting uncertainty may lead to completely different results; therefore, uncertainty management is a major issues in simulation-optimization. Because of its wide field of applications, simulation-optimiz…
This book introduces methods for uncertain multi-attribute decision making including uncertain multi-attribute group decision making and their applications to supply chain management, investment decision making, personnel assessment, redesigning products, maintenance services, military system efficiency evaluation. Multi-attribute decision making, also known as multi-objective decision making w…
This book is intended to present the milestones in the progression of uncertain Data envelopment analysis (DEA). Chapter 1 gives some basic introduction to uncertain theories, including probability theory, credibility theory, uncertainty theory and chance theory. Chapter 2 presents a comprehensive review and discussion of basic DEA models. The stochastic DEA is introduced in Chapter 3, in which…
Choosing an uncemented femoral prosthesis means first choosing a concept and to be effective, an operator has to have access to all the information that will allow them to reach the desired goals. This is the first step to be made. The quality of a surgical procedure does not depend on the manual skills of the surgeon performing it, but on how he has prepared and performed the operation “v…
This book describes the process of completing an NIH R01 grant application. It begins with the formation of an idea and proceeds through the subsequent stages: verifying the idea’s strength and potential, collecting high-quality preliminary data, networking for feedback, writing the first and subsequent drafts of the application (including details on what to include and tips on content and t…
Individual turnpike results are of great interest due to their numerous applications in engineering and in economic theory; in this book the study is focused on new results of turnpike phenomenon in linear optimal control problems. The book is intended for engineers as well as for mathematicians interested in the calculus of variations, optimal control and in applied functional analysis. Two…
This volume covers the topics presented at the 3rd International Conference on Tumor Microenvironment and Cellular Stress by an international community of researchers. The conference brings together scientists to discuss different cellular and animal models of tumor microenvironment study and identify common pathways that are candidates for therapeutic intervention; stimulate collaboration betw…