The idea of combining drugs and diagnostics in oncology is not new. When the selective estrogen-receptor modulator tamoxifen was developed in the 1970s for the treatment of breast cancer, data on estrogen-receptor status were correlated with the treatment outcome. Based on a phase II study performed in patients with advanced breast cancer, published in 1976, the investigators concluded:“a h…
The field of robotic vision has advanced dramatically recently with the development of new range sensors. Tremendous progress has been made resulting in significant impact on areas such as robotic navigation, scene/environment understanding, and visual learning. This edited book provides a solid and diversified reference source for some of the most recent important advancements in the field of …
This book contains a selection of articles from The 2016 World Conference on Information Systems and Technologies (WorldCIST'16), held between the 22nd and 24th of March at Recife, Pernambuco, Brazil. WorldCIST is a global forum for researchers and practitioners to present and discuss recent results and innovations, current trends, professional experiences and challenges of modern Information S…
This volume collects selected contributions from the “Fourth Tetrahedron Workshop on Grid Generation for Numerical Computations”, which was held in Verbania, Italy in July 2013. The previous editions of this Workshop were hosted by the Weierstrass Institute in Berlin (2005), by INRIA Rocquencourt in Paris (2007), and by Swansea University (2010). This book covers different, though related,…
Since the 2008 economic crisis, small and medium-sized enterprises (SMEs) have faced serious financial problems and have been looking to financial institutions and governments for solutions and new proposals to address these issues. This book examines the new challenge in which firms receive sustainable funding that is in alignment with the company’s spending capacity. The purpose of this boo…
In this book a neural network learning method with type-2 fuzzy weight adjustment is proposed. The mathematical analysis of the proposed learning method architecture and the adaptation of type-2 fuzzy weights are presented. The proposed method is based on research of recent methods that handle weight adaptation and especially fuzzy weights. The internal operation of the neuron is changed to wo…
Pulp and paper mill industries are always associated with the disposal problem of highly contaminated sludge or bio-solids. The development of innovative systems to maximize recovery of useful materials and/or energy in a sustainable way has become necessary. The management of wastes, in particular of industrial waste, in an economically and environmentally acceptable manner is one of the…
This book assesses the achievements of the software engineering discipline as represented by IT vendors in Japan in order to deepen understanding of the mechanisms of how software engineering capabilities relate to IT vendors’ business performance and business environment from the perspective of innovation and engineering management. Based on the concepts of service science and science for so…
Thyroid cancer is the most common malignant endocrine tumor and is the seventh most common cancer seen in throughout out the world. The incidence of thyroid cancer has been increasing more rapidly than any other cancer in many of the cancer registries from different parts of the world. Although the majority of thyroid cancers have an indolent biological behaviour, different histological types …
Situated at the forefront of interdisciplinary research on ferromagnetic microwires and their multifunctional composites, this book starts with a comprehensive treatment of the processing, structure, properties and applications of magnetic microwires. Special emphasis is placed on the giant magnetoimpedance (GMI) effect, which forms the basis for developing high-performance magnetic sensors. Af…