This open access edited volume introduces the concept of causal mechanisms to explore new ways of explaining the global dynamics of social policy, and shows that a mechanism-based approach provides several advantages over established approaches for studying social policy. The introductory chapter outlines the mechanism-based approach, which stands out by modularisation and a clear focus on acto…
This book serves as a comprehensive introductory guide to the practical aspects of risk assessment. Chapters include clearly defined objectives and summaries. The book includes: hazard identification, dose-response, exposure assessment, risk characterization, chemical mixtures, epidemiology, emerging issues and global perspectives with accessible language. The book concludes with a set of hypot…
This book serves as a timely and comprehensive overview of the latest science for perfluoroalkyl and polyfluoroalkyl substances (PFASs), covering the development of methods for assessing PFASs in biological fluids and tissues as well as the current knowledge regarding their toxicity to vertebrate organisms. This book includes chapters on human and wildlife exposure/body burdens, reviews of meta…
This powerful resource identifies wide-scale health challenges facing a rapidly urbanizing planet--including key concerns in nutrition, health status, health care, and safety--and strategies toward possible solutions. Theoretical and empirical analysis focuses on maximizing the benefits of urban living and minimizing negative outcomes across areas for improvement (health education, maternal and…
This briefs integrates and synthesizes an array of research about who helps others and under what conditions and discusses the implications of this research for a bystander intervention focused prevention agenda to reduce sexual and relationship violence in schools and communities. It combines an examination of bystander helping behavior in the specific context of sexual and relationship violen…
This book offers a comprehensive guide to total knee arthroplasty (TKA) that will assist in achieving excellent outcomes based on a sound understanding and technique. After an introductory section on the native knee that covers the anatomy, physiology, biomechanics, and patterns of disease, all aspects of primary knee arthroplasty are discussed in detail. Individual chapters are devoted to topi…
This book brings together selected peer-reviewed contributions from various research fields in statistics, and highlights the diverse approaches and analyses related to real-life phenomena. Major topics covered in this volume include, but are not limited to, bayesian inference, likelihood approach, pseudo-likelihoods, regression, time series, and data analysis as well as applications in the…
This direct, accessible guide uses a human rights perspective to define effectiveness in aid delivery and offer a robust framework for creating sustainable health programs and projects and assessing their progress. Geared toward hands-on professionals in such critical areas as food aid, maternal health, and disease control, it lays out challenges and solutions related to funding, planning, and …
Applied Survival Analysis Using R covers the main principles of survival analysis, gives examples of how it is applied, and teaches how to put those principles to use to analyze data using R as a vehicle. Survival data, where the primary outcome is time to a specific event, arise in many areas of biomedical research, including clinical trials, epidemiological studies, and studies of animals. Ma…
This volume is a unique combination of papers that cover critical topics in biostatistics from academic, government, and industry perspectives. The 6 sections cover Bayesian methods in biomedical research; Diagnostic medicine and classification; Innovative Clinical Trials Design; Modelling and Data Analysis; Personalized Medicine; and Statistical Genomics. The real world applications are in cli…