Thirty years ago when Sir Richard Branson called up Boeing and asked if they had a spare 747, few would have predicted the brash entrepreneur would so radically transform the placid business of air travel. But today, Branson flies airlines on six continents, employs hundreds of jets and, in 2014, was predicting that his spaceship company – Virgin Galactic – would soon open the space frontie…
This book takes a quantitative look at ICT-generated event data to highlight current trends and issues in Nigeria at the local, state and national levels. Without emphasizing a specific policy or agenda, it provides context and perspective on the relative spatial-temporal distribution of conflict factors in Nigeria. The analysis of violence at state and local levels reveals a fractal pattern of…
This book provides a comprehensive introduction to performing meta-analysis using the statistical software R. It is intended for quantitative researchers and students in the medical and social sciences who wish to learn how to perform meta-analysis with R. As such, the book introduces the key concepts and models used in meta-analysis. It also includes chapters on the following advanced topics: …
An argument that the development of scientific practice and growth of scientific knowledge are governed by Darwin's evolutionary model of descent with modification. Although scientific investigation is influenced by our cognitive and moral failings as well as all of the factors impinging on human life, the historical development of scientific knowledge has trended toward an increasingly accu…
How epidemic photography during a global pandemic of bubonic plague contributed to the development of modern epidemiology and our concept of the “pandemic.” In Visual Plague, Christos Lynteris examines the emergence of epidemic photography during the third plague pandemic (1894–1959), a global pandemic of bubonic plague that led to over twelve million deaths. Unlike medical photography…
In praise of imperfection: how life on our planet is a catalog of imperfections, errors, alternatives, and anomalies. In the beginning, there was imperfection, which became the source of all things. Anomalies and asymmetries caused planets to take shape from the bubbling void and sent light into darkness. Life on earth is a catalog of accidents, alternatives, and errors that turned out to wo…
The biological power of the placebo effect. The power of placebos to ameliorate symptoms has been with us for centuries. Western medicine today is finding it increasingly difficult to ignore the efficacy of placebos. In some clinical trials with placebos as controls, inert or sham replicas of active pharmaceutical drugs and even sham surgeries have been found to be as beneficial as the inter…
How the FDA was shaped by public health crises and patient advocacy, told against a background of the contentious hearings on the breast cancer drug Avastin. Food and Drug Administration approval for COVID-19 vaccines and the controversial Alzheimer's drug Aduhelm made headlines, but few of us know much about how the agency does its work. Why is the FDA the ultimate US authority on a drug's …
A lavishly illustrated guide to the magnum opus of the great seventeenth-century anatomist, master embalmer, artist, and collector of specimens. Frederik Ruysch (1638–1731) was a celebrated Dutch anatomist, master embalmer, and museologist. He is best remembered today for strange tableaux, crafted from fetal skeletons and other human remains, that flicker provocatively at the edges of scie…
How science is opening up the mysteries of the heart, revealing the poetry in motion within the machine. Your heart is a miracle in motion, a marvel of construction unsurpassed by any human-made creation. It beats 100,000 times every day—if you were to live to 100, that would be more than 3 billion beats across your lifespan. Despite decades of effort in labs all over the world, we have no…