Fungi produce many chemically diverse secondary metabolites whose biological roles largely remain elusive. Within the increasing number of sequenced fungal genomes several important genes involved in secondary metabolite formation have been identified. Most of these genes are clustered and their coordinated transcription is controlled in a complex way by both narrow pathway-specific regulators …
Alterations of thyroid function, especially hypothyroidism, are exceptionally common conditions. Studies from several developed countries revealed the prevalence of subclinical and overt hypothyroidism to be between 5 and 15 % and between 1 and 10%, respectively. Diagnosis and treatment of (overt or subclinical) hypothyroidism are considered to be easy tasks, since thyrotropin (TSH) concentrati…
This publication addresses the global challenges of food and water security in a rapidly changing and complex world. The essays highlight the links between bio-physical and socio-cultural processes, making connections between local and global scales, and focusing on the everyday practices of eating and drinking, essential for human survival. Written by international experts, each contribution i…
Leak Detection: Technology and Implementation assists water utilities with the development and implementation of leak detection programs. Leak detection and repair is one of the components of controlling water loss. In addition, techniques are discussed within this book and relevant case studies are presented. The book provides useful and practical information on leakage issues.
Instead of a focus on what is often described as Canada’s national pastime, contributors examine sports in Canadian literature that are decidedly not hockey. From skateboarding and parkour to fly fishing and curling, these essays engage with Canadian histories and broader societal understandings through sports on the margin. Interspersed with original reflections by iconic Canadian literary f…
This volume builds on Grant’s earlier analysis of Van Gogh’s correspondence, The Letters of Vincent van Gogh: A Critical Study (AU Press, 2014), a study in which he approached the letters from a literary critical standpoint, delving into key patterns of metaphors and concepts. In the present volume, he provides instead a literary theoretical analysis of the letters, one that draws them more…
The CK-12 foundation defines a flexbook as a “free and open source textbook platform where one can build and edit collaborative textbooks1 .” The FNDH 400 (formerly HN 400, department changed its name from Human Nutrition to Food, Nutrition, Dietetics and Health) Flexbook fits this definition, but I felt the name was particularly accurate due to the flexibility of Google Docs that it w…
When he died at the age of thirty-seven, Vincent van Gogh left a legacy of over two thousand artworks, for which he is now justly famous. But van Gogh was also a prodigious writer of letters—more than eight hundred of them, addressed to his parents, to friends such as Paul Gauguin, and, above all, to his brother Theo. His letters have long been admired for their exceptional literary quality, …
Computer assisted surgery systems intraoperatively support the surgeon by providing information on the location of hidden risk and target structures during surgery. However, soft tissue deformations make intraoperative registration (and thus intraoperative navigation) difficult. In this work, a novel, biomechanics based approach for real-time soft tissue registration from sparse intraoperative …
he skin is the largest organ of the body and serves as a barrier between the inner and external environments. As such, any problems in the skin can have serious effects on systemic health and well-being. Several studies have established that both nutritional and dietary factors play an important role in the maintenance of normal skin integrity, and can execute a causative, preventative and/or t…