Targeting the Broadly Pathogenic Kynurenine Pathway

Tryptophan metabolism via kynurenine pathway plays a critical role in both health and a variety of human diseases. This book highlights the known associations between kynurenine pathway and various disease states, as well as examines the current status of drug development and clinical trials of compounds known to alter tryptophan metabolism. The research plays a critical role in molecular targe…

Evolutionary Bioinformatics

Now in its third edition and supplemented with more online material, this book aims to make the "new" information-based (rather than gene-based) bioinformatics intelligible both to the "bio" people and the "info" people. Books on bioinformatics have traditionally served gene-hunters, and biologists who wish to construct family trees showing tidy lines of descent. While dealing extensively with …

Evolution of the Protein Synthesis Machinery and Its Regulation

The “omics” era has given a new perspective to the findings on the origin and evolution of the process of translation. This book provides insight into the evolution of the translation process and machinery from a modern perspective. Written by leading experts in molecular biology, this text looks into the origins and evolution of the protein synthetic machinery.

Mitochondrial Mechanisms of Degeneration and Repair in Parkinson's Disease

Edition

1

ISBN/ISSN

978-3-319-42137-7

Collation

XII, 275

Series Title

-

Call Number

-

Modern Climate Change Science

Composed of two extensive sections, this book surveys important work in climate change science, mainly in the United States, and introduces contributions to the body of science that have arrived on the scene between January 2013 and February 2014. The opening section offers a broad examination of contemporary climate change science, with subsections on the Intergovernmental Panel on Climate …

Multifaceted Roles of Crystallography in Modern Drug Discovery

The present work offers a snapshot of the state-of-the-art of crystallographic, analytical, and computational methods used in modern drug design and development. Topics discussed include: drug design against complex systems (membrane proteins, cell surface receptors, epigenetic targets, and ribosomes); modulation of protein-protein interactions; the impact of small molecule structures in drug d…

Modeling and Stochastic Learning for Forecasting in High Dimensions

The chapters in this volume stress the need for advances in theoretical understanding to go hand-in-hand with the widespread practical application of forecasting in industry. Forecasting and time series prediction have enjoyed considerable attention over the last few decades, fostered by impressive advances in observational capabilities and measurement procedures. On June 5-7, 2013, an internat…

Modelling and Control of Dynamic Systems Using Gaussian Process Models

This monograph opens up new horizons for engineers and researchers in academia and in industry dealing with or interested in new developments in the field of system identification and control. It emphasizes guidelines for working solutions and practical advice for their implementation rather than the theoretical background of Gaussian process (GP) models. The book demonstrates the potential of …

Multi-Component and Sequential Reactions in Polymer Synthesis

The series Advances in Polymer Science presents critical reviews of the present and future trends in polymer and biopolymer science. It covers all areas of research in polymer and biopolymer science including chemistry, physical chemistry, physics, material science. The thematic volumes are addressed to scientists, whether at universities or in industry, who wish to keep abreast of the importan…

Modelling Electroanalytical Experiments by the Integral Equation Method

This comprehensive presentation of the integral equation method as applied to electro-analytical experiments is suitable for electrochemists, mathematicians and industrial chemists. The discussion focuses on how integral equations can be derived for various kinds of electroanalytical models. The book begins with models independent of spatial coordinates, goes on to address models in one dimensi…