This book constitutes the refereed proceedings of the 12th International Colloquium on Theoretical Aspects of Computing, ICTAC 2015, held in Cali, Colombia, in October 2015. The 25 revised full papers presented together with 7 invited talks, 3 tool papers, and 2 short papers were carefully reviewed and selected from 93 submissions. The papers cover various topics such as algebra and category…
This annual report is a call to action to recognize the things that are having an impact on the internet today, and to embrace the notion that we as humans can change how we make money, govern societies, and interact with one another online. We invite you to participate in setting an agenda for how we can work together to create an internet that truly puts people first.This book is neither a co…
Phosphatases, such as TNAP are fundamental in regulating the roles of cellular, and consequently numerous body functions. TNAP is a ubiquitous enzyme with a wide spectrum of substrates and specificity. Regulation at the cellular level and the lack of TNAP activity is a lethal condition. Recent findings of a highly specific regional, laminar and subcellular localization of TNAP in the cerebral c…
This book gathers and updates the most significant advances of the last two centuries and presents an unprecedented micro paleontological study covering more than 20 stratigraphic sections. This information is supplemented by numerous sedimentological observations and analyses, on the basis of which a new lithostratigraphic framework for the Neogene of the Chacoparanense Basin is proposed.The b…
As indicated by its title, this monograph deals chiefly with morphologically recognizable deviations from the normal anatomical condition of the human CNS. The AD-associated pathology is illustrated from its beginnings (sometimes even in childhood) to its final form, which is reached late in life. The AD process commences much earlier than the clinically recognizable phase of the disorder, and …
This book deals with methods of measurement and evaluation of environmental noise based on an auditory neural and brain-oriented model. The model consists of the autocorrelation function (ACF) and the interaural cross-correlation function (IACF) mechanisms for signals arriving at the two ear entrances. Even when the sound pressure level of a noise is only about 35 dBA, people may feel annoyed d…
The challenge of housing is increasingly recognised in international policy discussions in connection to the processes of migration, climate change, and economic globalisation. This book addresses the challenges of housing and emerging solutions along the lines of three major dynamics: migration, climate change, and neo-liberalism. It explores the outcomes of neo-liberal »enabling« ideas, res…
The book presents a new, powerful model of neuronal networks, consisting of a three-dimensional neuronal culture in which 3D neuronal networks are coupled to micro-electrode-arrays (MEAs). It discusses the main advantages of the three-dimensional system compared to its two-dimensional counterpart, and shows that the network dynamics, recorded during both spontaneous and stimulated activity, dif…
This comprehensive volume is the first to specifically target developing, adult and diseased neural stem cells. It explores recent advances in the understanding of neural stem cell biology along with strategies that use these cells to tackle neurological diseases and brain aging. Ten inclusive chapters discuss a wide range of topics including neurogenesis, neurodegeneration, demyelinating disea…
Längst gibt es altersgerechte digitale Assistenzsysteme. Doch sind Umfang und Geschwindigkeit ihrer Verbreitung sowohl in Pflegeeinrichtungen als auch in privaten Haushalten weitgehend unbekannt. Informationen zu tatsächlich eingesetzten Systemen, realisierten Umsätzen und Marktvolumen sind kaum zu finden. Obwohl es viele Vermutungen hinsichtlich der Hindernisse bei der Einführung altersger…