The book is intended as an advanced undergraduate or first-year graduate course for students from various disciplines, including applied mathematics, physics and engineering. It has evolved from courses offered on partial differential equations (PDEs) over the last several years at the Politecnico di Milano. These courses had a twofold purpose: on the one hand, to teach students to appreciate t…
This volume explores the epigenetic alterations and their association with various human cancers. Considering one of human cancer as an example, individual chapters are focused on defining the role of epigenetic regulators and underlying mechanisms in cancer growth and progression. Epigenetic alteration including DNA methylation, histone modification, nucleosome positioning and non-coding R…
This book offers an in-depth examination of labor pain and analgesia with the aim of promoting natural childbirth without pain. All aspects of the subject are covered, including the latest techniques of delivering labor analgesia. Importantly, emphasis is placed on a holistic approach, detailed attention being paid to the humanization of childbirth and behavioral aspects in addition to evidence…
In this book, leading figures in the field of Developmental Origins of Health and Disease provide up-to-date information from human clinical trials, cohorts, and animal physiology experiments to reveal the interdependence between parental obesity and health of the offspring. Obesity of the mother and father produces obesity in their offspring, so we are caught up in an intergenerational cycle, …
This book covers the latest developments in enzyme immobilization with its wide applications, such as for industry, agriculture, medicine, and the environment. Topics covered include basics of enzyme immobilization, its implication in therapeutics and disease diagnostics, and its significance in solving environmental problems. This is an ideal book for researchers, graduate and postgraduate stu…
This book considers specific inferential issues arising from the analysis of dynamic shapes with the attempt to solve the problems at hand using probability models and nonparametric tests. The models are simple to understand and interpret and provide a useful tool to describe the global dynamics of the landmark configurations. However, because of the non-Euclidean nature of shape spaces, distri…
This book presents an experimental simulation of sewage treatment, which is designed to evaluate the environmental and social-economic impacts of integrated sewage treatment policies. The author puts forward a comprehensive linear optimization simulation model that takes the environmental, energy and economic systems into consideration. Beijing was selected as a typical Chinese city for the pur…
The Earth system consists of subsystems that include the atmosphere, hydrosphere (water), geosphere (rocks, minerals), biosphere, and humans. In order to understand these subsystems and their interactions, it is essential to clarify the mass transfer mechanism, geochemical cycle, and influence of human activity on the natural environment. This book presents fundamental theories (thermodynamics,…
This comprehensive textbook presents a clean and coherent account of most fundamental tools and techniques in Parameterized Algorithms and is a self-contained guide to the area. The book covers many of the recent developments of the field, including application of important separators, branching based on linear programming, Cut & Count to obtain faster algorithms on tree decompositions, algorit…
This volume provides insights into current research on fungal populations, communities and their interactions with other organisms. It focuses on fungal responses to the physical environment; interactions with bacteria, other fungi, invertebrates and plants; the role of fungi in ecosystem processes such as decomposition and nutrient cycling; and aspects of biogeography and conservation. Since …