This comprehensive volume presents data describing the role of oxidative stress in anterior eye disease. The content is divided into three logical parts: basic science of the cornea, basic science of the lens, and clinical practices. The first two parts include eighteen chapters that discuss topics ranging from oxidative stress and dry eye disease, endogenous protection of corneal cells against…
This authoritative volume reviews clinical, pathophysiological and therapeutic aspects of oxidative and nitrosative stress in different psychiatric disorders such as schizophrenia, bipolar disorder, autism, and attention deficit hyperactivity disorder (ADHD). Twenty-nine comprehensive chapters are divided into three distinct sections: clinical aspects, pathophysiological aspects, and therapeuti…
This volume examines the current state of free radical biology as it impacts on hepatic disorders. It takes a thorough look at the relationship of oxidative stress in acute and chronic disease and takes into account factors like: redox biomarkers; antioxidant defense and protection; cell signaling, mutations; oxidative damage involving lipids, proteins and nucleic acids; membrane trafficking, i…
This book focuses on data describing the roles of free radicals and related reactive species, and antioxidants, in the causes and treatments of diseases, examining both clinical and pre-clinical trials, as well as basic research. The book is divided into sub-sections with chapters on toxicological mechanisms, agents that produce toxicity, and special topics including areas such as antioxidant s…
Meteor is a full stack application platform that makes it easy to build powerful, real time Web apps quickly. Introducing Meteor guides you through building top-quality Web apps in a fraction of the time using an application platform built for the modern web. This book takes you from installing the development environment all the way through deploying a live app, and everything in between. Intr…
This concise book is a quick start-up primer on the Gradle build and release tool. You'll learn about Gradle and how to set it up to use. You'll learn about the Gradle life cycle and how to effectively leverage and use it. Also, you'll learn the basics of using site plugins and generating Javadocs, test coverage/FindBugs reports, version/release notes and more. Furthermore, you'll take advantag…
This volume contains the best papers presented at the 2nd ECCOMAS International Conference on Multiscale Computations for Solids and Fluids, held June 10-12, 2015.
This book constitutes the thoroughly refereed post-workshop proceedings of the 4th International Workshop on Structured Object-Oriented Formal Language and Method, SOFL+MSVL 2014, held in Luxembourg, Luxembourg, in November 2014. The 12 papers presented in this volume were carefully reviewed and selected from 20 submissions. They are organized in topical sections on testing and inspection; mode…
This book portrays the commonality of tissue micro-structure that dictates physiological function in various organs (microstructure-function relation). Tissue and organ models are used to illustrate physiological functions based on microstructure. Fiber scale properties such as orientation and crimp are described in detail. Structurally-based constitutive models are given throughout the book, n…
The purpose of this book is to summarize new insights on the structure and function of mountain ecosystems and to present evidence and perspectives on the impact of climate change on biodiversity. This volume describes overall features of high-mountain ecosystems in Japan, which are characterized by clear seasonality and snow-thawing dynamics. Individual chapters cover a variety of unique topic…